Catherine Murphy's directory photo.

Catherine Murphy


Primary Affiliation

Molecular Design and Engineering


Status Affiliate Faculty

Home Department of Chemistry

Phone 333-7680



  • Biography

    Professor Catherine Murphy is the Larry Faulkner Endowed Chair in Chemistry at Illinois. She also is associate director of the Materials Research Lab and is affilated with the Beckman Institute, the Department of Materials Science and Engineering, the Holonyak Micro and Nanotechnology Lab, and the Cancer Center.

    She earned two B.S. degrees, one in chemistry and one in biochemistry, from the University of Illinois in 1986. She received her Ph.D. from the University of Wisconsin in 1990. From 1990-1993, she was first an NSF and then an NIH postdoctoral fellow at the California Institute of Technology. From 1993-2009 Professor Murphy was a faculty member in the Department of Chemistry and Biochemistry at the University of South Carolina. In August 2009 she joined the faculty of the Department of Chemistry at the University of Illinois.

  • Honors

    TREE Award, Research Corporation for Science Advancement (2015); Member, U.S. National Academy of Sciences (2015); Fellow, Royal Society of Chemistry (2014); Carol Tyler Award, International Precious Metals Institute (2013); James D. & Julia P. Morrison Lectureship, Carleton College (2012); Fellow, American Chemical Society (2011); Lucy W. Pickett Lecturer, Mount Holyoke College (2011); Inorganic Nanoscience Award, given by the Division of Inorganic Chemistry, American Chemical Society, (2011); AAAS Fellow (2008); USC Russell Award for Research in Science, Mathematics, and Engineering (2005); Outstanding Undergraduate Research Mentor Award, University of South Carolina (2003); Golden Key Faculty Award for the Integration of Research and Undergraduate Teaching (1998); Camille Dreyfus Teacher-Scholar Award (1998-2000); Alfred P. Sloan Foundation Research Fellow (1997-1999); Cottrell Scholar Award (1996-2001); National Science Foundation CAREER Award (1995-1998).

  • 2017

    • Abtahi, S.M.H.; Burrows, N. D.; Idesis, F. A.; Murphy, C. J.; Saleh, N. B.; Vikesland, P. J. Sulfate Mediated End-to-End Assembly of Gold Nanorods, Langmuir 2017, 33, 1486-1495.
    • Burrows, N. D.; Harvey, S.; Idesis, F. A.; Murphy, C. J. Understanding the Seed-Mediated Growth of Gold Nanorods through a Fractional Factorial Design of Experiments, Langmuir, 2017 in press.
    • Falagan-Lotsch, P.; Grzincic, E. M.; Murphy, C. J. New Advances in Nanotechnology-based Diagnosis and Therapeutics for Breast Cancer: An Assessment of Active-Targeting Inorganic Nanoplatforms, Bioconjugate Chem. 2017, 28, 135-152.
    • Qiu, T. A.; Nguyen, T.H. T. ; Hudson-Smith, N. V.; Clement, P. L.; Forester, D.; Frew, H.; Hang, M.N.; Murphy, C. J.; Hamers, R. J.; Feng, Z. V.; Haynes, C. L. Growth-Based Bacterial Viability Assay for Interference-free and High-Throughput Toxicity Screening of Nanomaterials, Anal. Chem. 2017, 89, 2057-2064.
    • Qiu, T. A.; Torelli, M. D.; Vartanian, A. M.; Rackstraw, N. B.; Buchman, J. T.; Jacob, L. M.; Murphy, C. J.; Hamers, R. J.; Haynes, C. L. Quantification of Free Polyelectrolytes Present in Colloidal Suspension Reveals Source of Toxic Responses for Polyelectrolyte-wrapped Gold Nanoparticles, Anal. Chem. 2017, 89, 1823-1830.


    • Abadeer, N. S.; Murphy, C. J. Recent Progress in Cancer Thermal Therapy Using Gold Nanoparticles. J. Phys. Chem. C 2016, 120, 4691-4716.
    • Afrooz, A. R. M. N.; Das, D.; Murphy, C. J.; Vikesland, P.; Saleh, N. B. Co-Transport of Gold Nanospheres with Single-Walled Carbon Nanotubes in Saturated Porous Media, Water Res. 2016, 99, 7-15.
    • Burrows, N. D.; Lin, W.; Hinman, J. G.; Dennison, J. M.; Vartanian, A. M.; Abadeer, N. S.; Grzincic, E. M.; Jacob, L. M.; Li, J.; Murphy, C. J. Surface Chemistry of Gold Nanorods, Langmuir 2016, 32, 9905-9921.
    • Burrows, N. D.; Vartanian, A. M.; Abadeer, N.S.; Grzincic, E. M.; Jacob, L. M.; Lin, W.; Li, J.; Dennison, J. M.; Hinman, J. G.; Murphy, C. J. Anisotropic Nanoparticles and Anisotropic Surface Chemistry, J. Phys. Chem. Lett. 2016, 7, 632-641.
    • Falagan-Lotsch, P.; Grzincic, E. M.; Murphy, C. J. One Low-Dose Exposure of Gold Nanoparticles Induces Long-Term Changes in Human Cells, Proc. Natl. Acad. Sci. USA 2016, 113, 13318-13323.
    • Gao, Z.; Burrows, N. D.; Valley, N. A.; Schatz, G. C.; Murphy, C. J.; Haynes, C. L. In Solution SERS Sensing Using Mesoporous Silica-Coated Gold Nanorods, Analyst 2016, 141, 5088-5095.
    • Grassian, V.H.; Haes, A. J.; Mudunkotuwa, I. A.; Demokritou, P.; Kane, A. B.; Murphy, C. J.; Hutchison, J. E.; Issacs, J. A.; Jun, Y.-S.; Karn, B.; Khondaker, S. I.; Larsen, S. C.; Lau, B. L. T.; Pettibone, J.; Sadik, O. A.; Saleh, N. B.; Teague, C. NanoEHS – Defining Fundamental Science Needs: No Easy Feat when the Simple Itself is Complex, Environ. Sci.: Nano 2016, 3, 15-27.
    • Hinman, J. G.; Stork, A. J.; Varnell, J. A.; Gewirth. A. A.; Murphy, C. J. Seed-Mediated Growth of Gold Nanorods: Towards Nanorod Matryoshkas, Faraday Disc. 2016, 191, 9-33.
    • Holden, P. A.; Gardea-Torresdey, J.; Klaessig, F.; Turco, R. F.; Mortimer, M.; Hund-Rinke, K.; Hubal, E. A. C.; Avery, D.; Barcelo, D.; Behra, R.; Cohen, Y.; Deydier-Stephan, L.; Ferguson, P. L.; Frenandes, T. F.; Harthorn, B. H.; Henderson, W. M.; Hoke, R. A.; Hristozov, D.; Johnston, J. M.; Kane, A. B.; Kapustka, L.; Keller, A. A.; Lenihan, H. S.; Lovell, W.; Murphy, C. J.; Nisbet, R. M.; Petersen, E. J.; Salinas, E. R.; Scheringer, M.; Sharma, M.; Speed, D. E.; Sultan, Y.; Westerhoff, P.; White, J. C.; Wiesner, M. R.; Wong, E. M.; Xing, B.; Horan, M. S.; Godwin, H. A.; Nel, A. E. Considerations of Environmentally Relevant Test Conditions for Improved Evaluation of Ecological Hazard of Engineered Nanomaterials, Environ. Sci. Technol. 2016, 50, 6124-6145.
    • Mahmoud, M.; Lohse, S. E.; Murphy, C. J.; Suslick, K. S. Identification of Nanoparticles with a Colorimetric Sensor Array, ACS Sensors 2016, 1, 17-21.
    • Melby, E.; Mensch, A.; Lohse, S. E.; Peng, D.; Orr, G.; Murphy, C. J.; Hamers, R. J.; Pedersen, J. Formation of Supported Lipid Bilayers Containing Model Rafts and Their Interaction with Gold Nanoparticles, Environ. Sci.: Nano 2016, 3, 45-55.
    • Troiano, J. M.; Kuech, T. R.; Vartanian, A. M.; Torelli, M. D.; Sen, A.; Jacob, L. M.; Hamers, R. J.; Murphy, C. J.; Pedersen, J. A.; Geiger, F. M. On Electronic and Charge Interference in Second Harmonic Generation Reponses from Gold Metal Nanoparticles at Supported Lipid Bilayers, J. Phys. Chem. C 2016, 120, 20659-20667.
    • Wu, X.; Ni, Y.; Zhu, J.; Burrows, N. D.; Murphy, C. J.; Dumitrica, T.; Wang, X. Thermal Transport across Surfactant Layers on Gold Nanorods in Aqueous Solution, ACS Appl. Mater. Interfac. 2016, 8, 10581-10589.


    • Abadeer, N. S.; Fulop, G.; Chen, S.; Kall, M.; Murphy, C. J. Interactions of Bacterial Lipopolysaccharides with Gold Nanorod Surfaces Investigated by Refractometric Sensing, ACS Appl. Mater. Interfac. 2015, 7, 24915-24925.
    • DeVetter, B. M.; Mukherjee, P.; Murphy, C. J.; Bhargava, R. Measuring binding kinetics of aromatic thiolated molecules with nanoparticles via surface-enhanced Raman spectroscopy, Nanoscale, 2015, 7, 8766-8775.
    • Dominguez, G. A.; Lohse, S. E.; Torelli, M. D.; Murphy, C. J.; Hamers, R. J.; Orr, G.; Klaper, R. D. Effects of Charge and Surface Ligand Properties of Nanoparticles on Oxidative Stress and Gene Expression within the Gut of Daphnia magna, Aquatic Toxicology 2015, 162, 1-9.
    • Feng, Z. V.; Gunsolus, I. L.; Qiu, T. A.; Hurley, K. R.; Nyberg, L. H.; Johnson, K. P.; Vartanian, A. M.; Jacob, L. M.; Lohse, S. E.; Torelli, M. D.; Hamers, R. J.; Murphy, C. J.; Haynes, C. L. Impacts of Gold Nanoparticle Charge and Ligand Type on Surface Binding and Toxicity to Gram-Negative and Gram-Positive Bacteria, Chem. Sci. 2015, 6, 5186-5196.
    • Grzincic, E. M.; Murphy, C. J. Gold Nanorods Indirectly Promote Migration of Metastatic Human Breast Cancer Cells in Three-Dimensional Cultures, ACS Nano 2015, 9, 6801-6816.
    • Grzincic, E. M.; Yang, J. A.; Drnevitch, J.; Lotsch, P. F.; Murphy, C. J. Global Transcriptometic Analysis of Model Human Cell Lines Exposed to Surface-Modified Gold Nanoparticles: The Effect of Surface Chemistry, Nanoscale 2015, 7, 1349-1362.
    • Jacobson, K. H.; Gunsolus, I. L.; Kuech, T.R., Jr.; Troiano, J. M.; Melby, E. S.; Lohse, S. E.; Hu, D.H.; Chrisler, W. B.; Murphy, C. J.; Orr, G.; Geiger, F. M.; Haynes, C. L.; Pedersen, J. A. Lipopolysaccharide Density and Structure Governs the Extent and Distance of Nanoparticle Interaction with Actual and Model Bacterial Membranes, Environ. Sci. Technol. 2015, 49, 10642-10650.
    • Lin, W.; Insley, T.; Tuttle, M. D.; Zhu, L.; Berthold, D. A.; Kral, P.; Rienstra, C. M.; Murphy, C. J. Control of Protein Orientation on Gold Nanoparticle Surfaces, J. Phys. Chem. C 2015, 119, 21035-21043.
    • Murph, S.; Murphy, C. J.; Leach, A.; Gall, K. A Possible Oriented Attachment Growth Mechanism for Silver Nanowire Formation, Cryst. Growth Des. 2015, 15, 1968-1974.
    • Murphy, C. J.; Buriak, J. M. Best Practices for the Reporting of Colloidal Inorganic Nanomaterials, Chem. Mater. 2015, 27, 4911-4913.
    • Murphy, C. J.; Vartanian, A. M.; Geiger, F. M.; Hamers, R. J.; Pedersen, J.; Cui, Q.; Haynes, C. L.; Carlson, E. E.; Hernandez, R.; Klaper, R. D.; Orr, G.; Rosenzweig, Z. Biological Responses to Engineered Nanomaterials: Needs for the Next Decade, ACS Central Science 2015, 1, 117-123
    • Qiu, T. A.; Bozich, J. S.; Lohse, S. E.; Vartanian, A. M.; Jacob, L. M.; Meyer, B. M.; Gunsolus, I. L.; Niemuth, N. J.; Murphy, C. J.; Haynes, C. L.; Klaper, R. D. Gene Expression as an Indicator of the Molecular Response and Toxicity in the Bacterium Shewanella oneidensis and the Water Flea Daphnia magna Exposed to Functionalized Gold Nanoparticles, Environ. Sci.: Nano 2015, 2, 615-629.
    • Rankin, J.; Neelakantan, N.; Lundberg, K.; Grzincic, E.; Murphy, C. J.; Suslick, K. Magnetic, Fluorescent, and Copolymeric Silicone Microspheres, Adv.Sci. 2015, 2, 1500114.
    • Torelli, M. D.; Putans, R. A.; Tan, Y.; Lohse, S. E.; Murphy, C. J.; Hamers, R. J. Quantitative Determination of Ligand Densities on Nanomaterials by X-Ray Photoelectron Spectroscopy, ACS Appl. Mater. Interfac. 2015, 7, 1720-1725.
    • Troiano, J. M.; Olenick, L. L.; Kuech T. R.; Melby, E. S.; Hu, D.; Lohse, S. E.; Mensch, A. C.; Dogangun, M.; Vartanian, A. M.; Torelli, M. D.; Ehimiaghe, E.; Walter, S. R.; Fu, L.; Anderton, C. R.; Zhu, Z.; Wang, H.; Orr, G.; Murphy, C. J.; Hamers, R. J.; Pedersen, J. A.; Geiger, F. M. Direct Probes of 4-nm Diameter Gold Nanoparticles Interacting with Supported Lipid Bilayers, J. Phys. Chem. B 2015, 119, 534-546.


    • Abadeer, N. S.; Brennan, M. R.; Wilson, W. L.; Murphy, C. J. Distance and Plasmon Wavelength Dependent Fluorescence of Molecules Bound to Silica-Coated Gold Nanorods, ACS Nano 2014, 8, 8392-8406.
    • Alkilany, A. M.; Bani Yaseen, A. I.; Park, J.; Eller, J. R.; Murphy, C. J. Facile Transfer of Gold Nanoparticles from Aqueous Solutions to Organic Solvents with Thiolated Poly(ethylene glycol), RSC Adv. 2014, 4, 52676-52679.
    • Alkilany, A. M.; Boulos, S. P.; Lohse, S. E.; Thompson, L. B.; Murphy, C. J. Homing-Peptide- Conjugated Gold Nanorods: How Good is Molecular Targeting and Display for Controlling Cellular Uptake and Proliferation? Bioconjugate Chem. 2014, 25, 1162-1171.
    • Bishop, L. M.; Tillman, A. S.; Geiger, F. M.; Haynes, C. L.; Klaper, R. D.; Murphy, C. J.; Orr, G.; Pedersen, J. A.; DeStefano, L.; Hamers, R. J. Enhancing Graduate Student Communication to General Audiences through Blogging about Nanotechnology and Sustainability, J. Chem. Ed. 2014, 91, 1600-1605.
    • Bogart, L. K,; Pourroy, G.; Murphy, C. J. Puntes, V.; Pellegrino, T.; Rosenblum, D.; Peer, D.; Levy, R. Nanoparticles for Imaging, Sensing, Therapeutic Intervention, ACS Nano 2014, 3107–3122.
    • Bozich, J. S.; Lohse, S. E.; Torelli, M. D.; Murphy, C. J.; Hamers, R. J.; Klaper, R. D. Surface Chemistry, Charge, and Ligand Type Impact the Toxicity of Gold Nanoparticles to Daphina magna, Environ. Sci.: Nano 2014, 1, 260-270.
    • DeVetter, B. M.; Bhargava, R.; Murphy, C. J., Computational Study of the Surface-Enhanced Raman Scattering from Silica-Coated Silver Nanowires. Photochemistry and Photobiology 2014, 90, (2), 415-418, DOI: 10.1111/php.12205.
    • DeVetter, B. M.; Sivapalan, S. T.; Patel, D.; Schlumerich, M.; Murphy, C. J.; Bhargava, R. Observation of Molecular Diffusion in Polyelectrolyte-Wrapped SERS Nanoprobes, Langmuir 2014, 30, 8931-8937.
    • Gunsolus, I.; Hu, D.; Mihai, C.; Lohse, S. E.; Lee, C-S.; Torelli, M.; Hamers, R. J.; Murphy, C. J.; Orr, G.; Haynes, C. L. Facile Method to Stain the Bacterial Cell Surface for Super-Resolution Fluorescence Microscopy, Analyst 2014, 139, 3174-3178.
    • Kim, D.; Campos, A. R.; Datt, A.; Gao, Z.; Rycenga, M.; Burrows, N. D.; Greeneltch, N. G.; Mirkin, C. A.; Murphy, C. J.; van Duyne, R. P.; Haynes, C. L. Microfluidic-SERS Devices for One Shot Limit-of-Detection, Analyst 2014, 3227-3234.
    • Mahmoudi, M.; Lohse, S. E.; Murphy, C. J.; Fathizadeh, A.; Montazeri, A.; Suslick, K. S., Variation of Protein Corona Composition of Gold Nanoparticles Following Plasmonic Heating. Nano Letters 2014, 14, (1), 6-12, DOI: 10.1021/nl403419e.
    • Yang, J. A.; Lin, W.; Woods, W. S.; George, J. M.; Murphy, C. J. a-Synuclein’s Adsorption, Conformation and Orientation on Cationic Gold Nanoparticle Surfaces Seeds Global Conformational Change, J. Phys. Chem. B 2014, 118, 3359-3571.


    • Boulos, S. P.; Prigozhin, M. B.; Liu, Y.; Wirth, A. J.; Boppart, S. A.; Gruebele, M.; Murphy, C. J. The Gold Nanorod-Biology Interface: From Proteins to Cells to Tissue, Curr. Phys. Chem. 2013, 3, 128-135. DOI:10.2174/1877946811303020002.
    • Shah, A. B.; Sivapalan, S. T.; DeVetter, B. M.; Yang, T. K.; Wen, J.; Bhargava, R.; Murphy, C. J.; Zuo, J-M. High-Index Facets in Gold Nanocrystals Elucidated by Coherent Electron Diffraction, NanoLetters 2013, 13, 1840-1846. DOI:10.1021/nl400609t.
    • Sivapalan, S. T.; DeVetter, B. M.; Yang, T. K.; Schulmerich, M. V.; Bhargava, R.; Murphy, C. J., Surface-Enhanced Raman Spectroscopy of Polyelectrolyte-Wrapped Gold Nanoparticles in Colloidal Suspension. Journal of Physical Chemistry C 2013, 117, (20), 10677-10682, DOI: 10.1021/jp402392y.
    • Sivapalan, S. T.; DeVetter, B. M.; Yang, T. K.; van Dijk, T.; Schulmerich, M. V.; Carney, P. S.; Bhargava, R.; Murphy, C. J. Off-resonance surface-enhanced Raman spectroscopy from gold nanorod suspensions as a function of aspect ratio: not what we thought, ACS Nano 2013, 7, 2099-2105. DOI:10.1021/nn305710k.
    • van Dijk, T.; Sivapalan, S. T.; DeVetter, B. M.; Yang, T. K.; Schulmerich, M. V.; Murphy, C. J.; Bhargava, R.; Carney, P. S. Competition Between Extinction and Enhancement if Surface- Enhanced Raman Spectroscopy, J. Phys. Chem. Lett. 2013, 3, 1193-1196. DOI: 10.1021/jz4005043.