Paul Kenis

Description

  • Title: Professor
  • Group: 3D Micro- and Nanosystems
  • Status: Beckman Part-time Faculty
  • Home: Chemical and Biomolecular Engineering

Address

Biography

Paul Kenis received his B.S. in Chemistry from the University of Nijmegen, The Netherlands, in 1993 and his Ph.D. in Chemical Engineering from the University of Twente, The Netherlands, in 1997. Next he was a postdoc at Harvard University with George Whitesides till 2000. Presently, he is an Assistant Professor in the Department of Chemical & Biomolecular Engineering at the University of Illinois and a part-time faculty member in the 3D Micro- and Nanosystems Group of the Beckman Institute. His research focuses on microchemical systems: microreactors, microfuel cells, and enabling microfluidic tools for other studies.

Honors

3M Young Faculty Award (2001 - 2005)
NSF CAREER Award (2005 - 2010)
Xerox Research Award, College of Engineering, UIUC (2006)
Excellence in Teaching Award, School of Chemical Sciences, UIUC (2006)Helen Corley Petit Scholar, College of Liberal Arts and Sciences, UIUC (2007 - 2008)
Beckman Fellow, Center for Advanced Study, UIUC (2007 - 2008)
SEBM’s 2008 Alan MacDiarmid Best Paper Award in interdisciplinary research (2008)
AICHE Separations Division best paper award (with Sarah Perry) (2009)
University Scholar, President’s office UIUC (2011)
William H. & Janet G. Lycan Professor, School of Chemical Sciences, UIUC (2013)

 

Research

Our research focuses on the development of microchemical systems. For example, we explore the utilization of multistream laminar flow in two types of electrochemical microreactors: (1) Membraneless fuel cells in which chemical energy is converted into electrical power; and (2) Microreactors that enable highly efficient electrochemical regeneration of cofactors for biocatalytic processes.

To date, microscale systems research has focused mostly on miniaturization of functional components, leaving miniaturization of long lifetime power sources as one of the major challenges. In our membraneless direct-liquid microfuel cells we exploit the occurrence of laminar flow at the microscale to keep the cathodic and anodic fuel streams separated while still in diffusional contact. These microfuel cells consist of a Y-shaped microfluidic channel design in which two liquid streams containing fuel and oxidant merge and continue to flow laminarly in parallel between two catalyst-covered electrodes on opposing walls. This eliminates the need for the polymer electrolyte membrane (PEM), typically Nafion, in traditional direct-liquid microfuel cells. In addition, through the flow rate and the channel geometry/dimensions the membrane-less design enables direct control over fuel crossover; a major issue in traditional direct methanol fuel cells.

The use of enzymes is an environmentally benign (green) approach to the production of chiral fine chemicals, including staring materials for pharmaceuticals, food additives, perfumes, etc. The stoichiometric use of cofactors such as NADH being cost prohibitive and an efficient method to regenerate cofactors for these enzymes being unavailable has prevented widespread use of biocatalyis in chemical processes. We are exploring the use of laminar flow to efficiently regenerate enzymatic cofactors in electrochemical microreactors.

Publications

  • 2016
    • Goyal, S.; Economou, A. E.; Papadopoulos, T.; Horstman, E. M.; Zhang, G. G. Z.; Gong, Y. C.; Kenis, P. J. A., Solvent Compatible Microfluidic Platforms for Pharmaceutical Solid Form Screening. RSC Advances 2016, 6, (16), 13286-13296.
    • Kim, B.; Hillman, F.; Ariyoshi, M.; Fujikawa, S.; Kenis, P. J. A., Effects of Composition of the Micro Porous Layer and the Substrate on Performance in the Electrochemical Reduction of Co2 to Co. Journal of Power Sources 2016, 312, 192-198.
    • Ma, S. C.; Sadakiyo, M.; Luo, R.; Heima, M.; Yamauchi, M.; Kenis, P. J. A., One-Step Electrosynthesis of Ethylene and Ethanol from Co2 in an Alkaline Electrolyzer. Journal of Power Sources 2016, 301, 219-228.
    • Oberst, J. L.; Jhong, H. R.; Kenis, P. J. A.; Gewirth, A. A., Insight into the Electrochemical Reduction of Co2 on Gold via Surface-Enhanced Raman Spectroscopy and N-Containing Additives. Journal of Solid State Electrochemistry 2016, 20, (4), 1149-1154.
    • Oruc, M. E.; Desai, A. V.; Nuzzo, R. G.; Kenis, P. J. A., Design, Fabrication, and Characterization of a Proposed Microchannel Water Electrolyzer. Journal of Power Sources 2016, 307, 122-128.
    • Oruc, M. E.; Desai, A. V.; Kenis, P. J. A.; Nuzzo, R. G., Comprehensive Energy Analysis of a Photovoltaic Thermal Water Electrolyzer. Applied Energy 2016, 164, 294-302.
    • See, G. G.; Naughton, M. S.; Xu, L.; Nuzzo, R. G.; Kenis, P. J. A.; Cunningham, B. T., Enhanced Emission of Quantum Dots Embedded within the High-Index Dielectric Regions of Photonic Crystal Slabs. Applied Physics Letters 2016, 108, (17).
    • Verma, S.; Lu, X.; Ma, S. C.; Masel, R. I.; Kenis, P. J. A., The Effect of Electrolyte Composition on the Electroreduction of Co2 to Co on Ag Based Gas Diffusion Electrodes. Physical Chemistry Chemical Physics 2016, 18, (10), 7075-7084.
    • Wright, B. D.; Whittenberg, J.; Desai, A.; DiFelice, C.; Kenis, P. J. A.; Lapi, S. E.; Reichert, D. E., Microfluidic Preparation of a Zr-89-Labeled Trastuzumab Single-Patient Dose. Journal of Nuclear Medicine 2016, 57, (5), 747-752.
  • 2015
    • Wu, K. N.; Birgersson, E.; Kim, B.; Kenis, P. J. A.; Karimi, I. A., Modeling and Experimental Validation of Electrochemical Reduction of CO2 to CO in a Microfluidic Cell. Journal of the Electrochemical Society 2015, 162, (1), F23-F32, DOI:10.1149/2.1021414jes.

    • Wu, K. N.; Birgersson, E.; Kim, B.; Kenis, P. J. A.; Karimi, I. A., Modeling and Experimental Validation of Electrochemical Reduction of CO2 to CO in a Microfluidic Cell (Vol 162, Pg F23, 2015). Journal of the Electrochemical Society 2015, 162, (3), X6-X6, DOI:10.1149/2.0341503jes.

    • See, G. G.; Xu, L.; Naughton, M. S.; Tang, T. T.; Bonita, Y.; Joo, J.; Trefonas, P.; Deshpande, K.; Kenis, P. J. A.; Nuzzo, R. G.; Cunningham, B. T., Region Specific Enhancement of Quantum Dot Emission Using Interleaved Two-Dimensional Photonic Crystals. Applied Optics 2015, 54, (9), 2302-2308, DOI:10.1364/Ao.54.002302.

    • Mohan, R.; Sanpitakseree, C.; Desai, A. V.; Sevgen, S. E.; Schroeder, C. M.; Kenis, P. J. A., A Microfluidic Approach to Study the Effect of Bacterial Interactions on Antimicrobial Susceptibility in Polymicrobial Cultures. RSC Advances 2015, 5, (44), 35211-35223, DOI:10.1039/C5ra04092b.

    • Maeki, M.; Pawate, A. S.; Yamashita, K.; Kawamoto, M.; Tokeshi, M.; Kenis, P. J. A.; Miyazaki, M., A Method of Cryoprotection for Protein Crystallography by Using a Microfluidic Chip and Its Application for in Situ X-Ray Diffraction Measurements. Analytical Chemistry 2015, 87, (8), 4194-4200, DOI:10.1021/ACS.analchem.5b00151.

    • Li, H. R.; Whittenberg, J. J.; Zhou, H. Y.; Ranganathan, D.; Desai, A. V.; Koziol, J.; Zeng, D. X.; Kenis, P. J. A.; Reichert, D. E., Development of a Microfluidic "Click Chip" Incorporating an Immobilized Cu(I) Catalyst. RSC Advances 2015, 5, (8), 6142-6150, DOI:10.1039/C4ra15507f.

    • Kim, B.; Ma, S.; Jhong, H. R. M.; Kenis, P. J. A., Influence of Dilute Feed and Ph on Electrochemical Reduction of CO2 to CO on Ag in a Continuous Flow Electrolyzer. Electrochimica Acta 2015, 166, 271-276, DOI:10.1016/j.electacta.2015.03.064.

    • Horstman, E. M.; Goyal, S.; Pawate, A.; Lee, G.; Zhang, G. G. Z.; Gong, Y. C.; Kenis, P. J. A., Crystallization Optimization of Pharmaceutical Solid Forms with X-Ray Compatible Microfluidic Platforms. Crystal Growth & Design 2015, 15, (3), 1201-1209, DOI:10.1021/Cg5016065.

    • Bhamidi, V.; Lee, S. H.; He, G. W.; Chow, P. S.; Tan, R. B. H.; Zukoski, C. F.; Kenis, P. J. A., Antisolvent Crystallization and Polymorph Screening of Glycine in Microfluidic Channels using Hydrodynamic Focusing. Crystal Growth & Design 2015, 15, (7), 3299-3306.
    • Horstman, E. M.; Bertke, J. A.; Kim, E. H.; Gonzalez, L. C.; Zhang, G. G. Z.; Gong, Y.; Kenis, P. J. A., Crystallization and Characterization of Cocrystals of Piroxicam and 2,5-Dihydroxybenzoic Acid. Crystengcomm 2015, 17, (28), 5299-5306.
    • Keswani, R. K.; Baik, J.; Yeomans, L.; Hitzman, C.; Johnson, A. M.; Pawate, A. S.; Kenis, P. J. A.; Rodriguez-Homedo, N.; Stringer, K. A.; Rosania, G. R., Chemical Analysis of Drug Biocrystals: A Role for Counterion Transport Pathways in Intracellular Drug Disposition. Molecular Pharmaceutics 2015, 12, (7), 2528-2536.
    • Kolossov, V. L.; Beaudoin, J. N.; Ponnuraj, N.; DiLiberto, S. J.; Hanafin, W. P.; Kenis, P. J. A.; Gaskins, H. R., Thiol-Based Antioxidants Elicit Mitochondrial Oxidation via Respiratory Complex III. American Journal of Physiology-Cell Physiology 2015, 309, (2), C81-C91.
    • Naughton, M. S.; Kumar, V.; Bonita, Y.; Deshpande, K.; Kenis, P. J. A., High Temperature Continuous Flow Synthesis of Cdse/Cds/Zns, Cds/Zns, and Cdses/Zns Nanocrystals. Nanoscale 2015, 7, (38), 15895-15903.
    • Pawate, A. S.; Srajer, V.; Schieferstein, J.; Guha, S.; Henning, R.; Kosheleva, I.; Schmidt, M.; Ren, Z.; Kenis, P. J. A.; Perry, S. L., Towards Time-Resolved Serial Crystallography in a Microfluidic Device. Acta Crystallographica Section F-Structural Biology Communications 2015, 71, 823-830.
    • Wright, B. D.; Whittenburg, J. J.; Desai, A.; Difelice, C.; Kenis, P.; Lapi, S. E.; Reichert, D., Microfluidic Labeling and Purification of Zr-89 and Cu-64 Labeled Herceptin. Journal of Labelled Compounds & Radiopharmaceuticals 2015, 58, S40-S40.
  • 2014
    • Byrne, M. B.; Kimura, Y.; Kapoor, A.; He, Y.; Mattam, K. S.; Hasan, K. M.; Olson, L. N.; Wang, F.; Kenis, P. J. A.; Rao, C. V., Oscillatory Behavior of Neutrophils under Opposing Chemoattractant Gradients Supports a Winner-Take-All Mechanism. Plos One 2014, 9, (1), DOI: 10.1371/journal.pone.0085726.

    • Goyal, S.; Desai, A. V.; Lewis, R. W.; Ranganathan, D. R.; Li, H. R.; Zeng, D. X.; Reichert, D. E.; Kenis, P. J. A., Thiolene and SIFEL-Based Microfluidic Platforms for Liquid-Liquid Extraction. Sensors and Actuators B-Chemical 2014, 190, 634-644, DOI: 10.1016/j.snb.2013.09.065.

    • Kolossov, V. L.; Hanafin, W. P.; Beaudoin, J. N.; Bica, D. E.; DiLiberto, S. J.; Kenis, P. J. A.; Gaskins, H. R., Featured Article: Inhibition of Glutathione Synthesis Distinctly Alters Mitochondrial and Cytosolic Redox Poise. Experimental Biology and Medicine 2014, 239, (4), 394-403, DOI: 10.1177/1535370214522179.

    • Li, H. R.; Zhou, H. Y.; Krieger, S.; Parry, J. J.; Whittenberg, J. J.; Desai, A. V.; Rogers, B. E.; Kenis, P. J. A.; Reichert, D. E., Triazine-Based Tool Box for Developing Peptidic Pet Imaging Probes: Syntheses, Microfluidic Radio Labeling, and Structure-Activity Evaluation. Bioconjugate Chemistry 2014, 25, (4), 761-772, DOI: 10.1021/bc500034n.

    • Ma, S. C.; Lan, Y. C.; Perez, G. M. J.; Moniri, S.; Kenis, P. J. A., Silver Supported on Titania as an Active Catalyst for Electrochemical Carbon Dioxide Reduction. Chemsuschem 2014, 7, (3), 866-874, DOI: 10.1002/cssc.201300934.

    • Mahadik, B. P.; Wheeler, T. D.; Skertich, L. J.; Kenis, P. J. A.; Harley, B. A. C., Microfluidic Generation of Gradient Hydrogels to Modulate Hematopoietic Stem Cell Culture Environment. Advanced Healthcare Materials 2014, 3, (3), 449-458, DOI: 10.1002/adhm.201300263.

    • Tice, J. D.; Desai, A. V.; Bassett, T. A.; Apblett, C. A.; Kenis, P. J. A., Control of Pressure-Driven Components in Integrated Microfluidic Devices Using an on-Chip Electrostatic Microvalve. RSC Advances 2014, 4, (93), 51593-51602, DOI:10.1039/C4ra10341f.

    • Perry, S. L.; Guha, S.; Pawate, A. S.; Henning, R.; Kosheleva, I.; Srajer, V.; Kenis, P. J. A.; Ren, Z., In Situ Serial Laue Diffraction on a Microfluidic Crystallization Device. Journal of Applied Crystallography 2014, 47, 1975-1982, DOI:10.1107/S1600576714023322.

    • Ma, S.; Luo, R.; Moniri, S.; Lan, Y. C.; Kenis, P. J. A., Efficient Electrochemical Flow System with Improved Anode for the Conversion of CO2 to CO. Journal of the Electrochemical Society 2014, 161, (10), F1124-F1131, DOI:10.1149/2.1201410jes.

    • Lopez-Montesinos, P. O.; Desai, A. V.; Kenis, P. J. A., A Three-Dimensional Numerical Model of a Micro Laminar Flow Fuel Cell with a Bridge-Shaped Microchannel Cross-Section. Journal of Power Sources 2014, 269, 542-549, DOI:10.1016/j.jpowsour.2014.06.127.

    • Lan, Y. C.; Ma, S. C.; Lu, J. X.; Kenis, P. J. A., Investigation of a Cu(Core)/CuO(Shell) Catalyst for Electrochemical Reduction of CO2 in Aqueous Soultion. International Journal of Electrochemical Science 2014, 9, (12), 7300-7308.

    • Lan, Y. C.; Ma, S. C.; Kenis, P. J. A.; Lu, J. X., Hydrogen Evolution in the Presence of CO2 in an Aqueous Solution During Electrochemical Reduction. International Journal of Electrochemical Science 2014, 9, (12), 8097-8105.

    • Lan, Y. C.; Gai, C.; Kenis, P. J. A.; Lu, J. X., Electrochemical Reduction of Carbon Dioxide on Cu/CuO Core/Shell Catalysts. Chemelectrochem 2014, 1, (9), 1577-1582, DOI:10.1002/celc.201402182.

    • Khvostichenko, D. S.; Schieferstein, J. M.; Pawate, A. S.; Laible, P. D.; Kenis, P. J. A., X-Ray Transparent Microfluidic Chip for Mesophase-Based Crystallization of Membrane Proteins and on-Chip Structure Determination. Crystal Growth & Design 2014, 14, (10), 4886-4890, DOI:10.1021/Cg5011488.

    • Byrne, M. B.; Trump, L.; Desai, A. V.; Schook, L. B.; Gaskins, H. R.; Kenis, P. J. A., Microfluidic Platform for the Study of Intercellular Communication via Soluble Factor-Cell and Cell-Cell Paracrine Signaling. Biomicrofluidics 2014, 8, (4), DOI:Artn 044104 DOI:10.1063/1.4887098.

    • Byrne, M. B.; Leslie, M. T.; Gaskins, H. R.; Kenis, P. J. A., Methods to Study the Tumor Microenvironment under Controlled Oxygen Conditions. Trends in Biotechnology 2014, 32, (11), 556-563, DOI:10.1016/j.tibtech.2014.09.006.

  • 2013
    • Appel, A. M.; Bercaw, J. E.; Bocarsly, A. B.; Dobbek, H.; DuBois, D. L.; Dupuis, M.; Ferry, J. G.; Fujita, E.; Hille, R.; Kenis, P. J. A.; Kerfeld, C. A.; Morris, R. H.; Peden, C. H. F.; Portis, A. R.; Ragsdale, S. W.; Rauchfuss, T. B.; Reek, J. N. H.; Seefeldt, L. C.; Thauer, R. K.; Waldrop, G. L., Frontiers, Opportunities, and Challenges in Biochemical and Chemical Catalysis of Co2 Fixation. Chemical Reviews 2013, 113, (8), 6621-6658, DOI: 10.1021/cr300463y.

    • Gabrielson, N. P.; Desai, A. V.; Mahadik, B.; Hofmann, M. C.; Kenis, P. J. A.; Harley, B. A. C., Cell-Laden Hydrogels in Integrated Microfluidic Devices for Long-Term Cell Culture and Tubulogenesis Assays. Small 2013, 9, (18), 3076-3081, DOI: 10.1002/smll.201203030.

    • Goyal, S.; Thorson, M. R.; Schneider, C. L.; Zhang, G. G. Z.; Gong, Y. C.; Kenis, P. J. A., A Microfluidic Platform for Evaporation-Based Salt Screening of Pharmaceutical Parent Compounds. Lab on a Chip 2013, 13, (9), 1708-1723, DOI: 10.1039/c3lc41271g.

    • He, Y.; Li, D.; Cook, S. L.; Yoon, M. S.; Kapoor, A.; Rao, C. V.; Kenis, P. J. A.; Chen, J.; Wang, F., Mammalian Target of Rapamycin and Rictor Control Neutrophil Chemotaxis by Regulating Rac/Cdc42 Activity and the Actin Cytoskeleton. Molecular Biology of the Cell 2013, 24, (21), 3369-3380, DOI: 10.1091/mbc.E13-07-0405.

    • Hollinger, A. S.; Kenis, P. J. A., Manufacturing All-Polymer Laminar Flow-Based Fuel Cells. Journal of Power Sources 2013, 240, 486-493, DOI: 10.1016/j.jpowsour.2013.04.053.

    • Jhong, H. R.; Brushett, F. R.; Kenis, P. J. A., The Effects of Catalyst Layer Deposition Methodology on Electrode Performance. Advanced Energy Materials 2013, 3, (5), 589-599, DOI: 10.1002/aenm.201200759.

    • Khvostichenko, D. S.; Kondrashkina, E.; Perry, S. L.; Pawate, A. S.; Brister, K.; Kenis, P. J. A., An X-Ray Transparent Microfluidic Platform for Screening of the Phase Behavior of Lipidic Mesophases. Analyst 2013, 138, (18), 5384-5395, DOI: 10.1039/c3an01174g.

    • Khvostichenko, D. S.; Ng, J. J. D.; Perry, S. L.; Menon, M.; Kenis, P. J. A., Effects of Detergent Beta-Octylglucoside and Phosphate Salt Solutions on Phase Behavior of Monoolein Mesophases. Biophysical Journal 2013, 105, (8), 1848-1859, DOI: 10.1016/j.bpj.2013.09.009.

    • Kolossov, V. L.; Beaudoin, J. N.; Hanafin, W. P.; DiLiberto, S. J.; Kenis, P. J. A.; Gaskins, H. R., Transient Light-Induced Intracellular Oxidation Revealed by Redox Biosensor. Biochemical and Biophysical Research Communications 2013, 439, (4), 517-521, DOI: 10.1016/j.bbrc.2013.09.011.

    • Mohan, R.; Mukherjee, A.; Sevgen, S. E.; Sanpitakseree, C.; Lee, J.; Schroeder, C. M.; Kenis, P. J. A., A Multiplexed Microfluidic Platform for Rapid Antibiotic Susceptibility Testing. Biosensors & Bioelectronics 2013, 49, 118-125, DOI: 10.1016/j.bios.2013.04.046.

    • Naughton, M. S.; Gu, G. H.; Moradia, A. A.; Kenis, P. J. A., Tailoring Electrode Hydrophobicity to Improve Anode Performance in Alkaline Media. Journal of Power Sources 2013, 242, 581-588, DOI: 10.1016/j.jpowsour.2013.05.054.

    • Naughton, M. S.; Tornow, C. E.; Bonita, Y.; Jhong, H. R.; Brushett, F. R.; Gewirth, A. A.; Kenis, P. J. A., In-Situ Measurement of Ethanol Tolerance in an Operating Fuel Cell. International Journal of Hydrogen Energy 2013, 38, (21), 8980-8991, DOI: 10.1016/j.ijhydene.2013.04.147.

    • Perry, S. L.; Guha, S.; Pawate, A. S.; Bhaskarla, A.; Agarwal, V.; Nair, S. K.; Kenis, P. J. A., A Microfluidic Approach for Protein Structure Determination at Room Temperature Via on-Chip Anomalous Diffraction. Lab on a Chip 2013, 13, (16), 3183-3187, DOI: 10.1039/c3lc50276g.

    • Salehi-Khojin, A.; Jhong, H. R. M.; Rosen, B. A.; Zhu, W.; Ma, S. C.; Kenis, P. J. A.; Masel, R. I., Nanoparticle Silver Catalysts That Show Enhanced Activity for Carbon Dioxide Electrolysis. Journal of Physical Chemistry C 2013, 117, (4), 1627-1632.

    • Thorson, M. R.; Siil, K. I.; Kenis, P. J. A., Effect of Cations on the Electrochemical Conversion of Co2 to CO. Journal of the Electrochemical Society 2013, 160, (1), F69-F74, DOI: 10.1149/2.052301jes.

    • Tice, J. D.; Bassett, T. A.; Desai, A. V.; Apblett, C. A.; Kenis, P. J. A., A Monolithic Poly(Dimethylsiloxane) Electrostatic Actuator for Controlling Integrated Pneumatic Microsystems. Sensors and Actuators A-Physical 2013, 196, 22-29, DOI: 10.1016/j.sna.2013.03.020.

    • Tice, J. D.; Rosheck, J. B.; Hamlin, C. D.; Apblett, C. A.; Kenis, P. J. A., Normally-Closed Electrostatic Microvalve Fabricated Using Exclusively Soft-Lithographic Techniques and Operated with Portable Electronics. Journal of Microelectromechanical Systems 2013, 22, (6), 1251-1253, DOI: 10.1109/jmems.2013.2282711.

    • Zeng, D. X.; Desai, A. V.; Ranganathan, D.; Wheeler, T. D.; Kenis, P. J. A.; Reichert, D. E., Microfluidic Radiolabeling of Biomolecules with Pet Radiometals. Nuclear Medicine and Biology 2013, 40, (1), 42-51.

  • 2012
    • Jhong, H. R.; Brushett, F. R.; Yin, L. L.; Stevenson, D. M.; Kenis, P. J. A., Combining Structural and Electrochemical Analysis of Electrodes Using Micro-Computed Tomography and a Microfluidic Fuel Cell. Journal of the Electrochemical Society 2012, 159, (3), B292-B298.

    • Brushett, F. R.; Naughton, M. S.; Ng, J. W. D.; Yin, L. L.; Kenis, P. J. A., Analysis of Pt/C Electrode Performance in a Flowing-Electrolyte Alkaline Fuel Cell. International Journal of Hydrogen Energy 2012, 37, (3), 2559-2570.

    • Desai, A. V.; Tice, J. D.; Apblett, C. A.; Kenis, P. J. A., Design Considerations for Electrostatic Microvalves with Applications in Poly(Dimethylsiloxane)-Based Microfluidics. Lab on a Chip 2012, 12, (6), 1078-1088.

    • Naughton, M. S.; Moradia, A. A.; Kenis, P. J. A., Quantitative Analysis of Single-Electrode Plots to Understand in-Situ Behavior of Individual Electrodes. Journal of the Electrochemical Society 2012, 159, (6), B761-B769.

    • Guha, S.; Perry, S. L.; Pawate, A. S.; Kenis, P. J. A., Fabrication of X-Ray Compatible Microfluidic Platforms for Protein Crystallization. Sensors and Actuators B-Chemical 2012, 174, 1-9

    • Chen, K.; Goh, L.; He, G.; Kenis, P. J. A.; Zukoski, C. F.; Braatz, R. D., Identification of Nucleation Rates in Droplet-Based Microfluidic Systems. Chemical Engineering Science 2012, 77, 235-241.

    • Goyal, S.; Thorson, M. R.; Zhang, G. G. Z.; Gong, Y. C.; Kenis, P. J. A., Microfluidic Approach to Cocrystal Screening of Pharmaceutical Parent Compounds. Crystal Growth & Design 2012, 12, (12), 6023-6034.

    • Kolossov, V. L.; Leslie, M. T.; Chatterjee, A.; Sheehan, B. M.; Kenis, P. J. A.; Gaskins, H. R., Forster Resonance Energy Transfer-Based Sensor Targeting Endoplasmic Reticulum Reveals Highly Oxidative Environment. Experimental Biology and Medicine 2012, 237, (6), 652-662.

    • Mahadik, B. P.; Haba, S. P.; Choi, J. S.; Kenis, P. A. J.; Harley, B. A. C., Building Bone Marrow: Engineering Biophysical Regulation of Hematopoietic Stem Cell Fate Decisions. Journal of Tissue Engineering and Regenerative Medicine 2012, 6, 278-278.

    • Thorson, M. R.; Brushett, F. R.; Timberg, C. J.; Kenis, P. J. A., Design Rules for Electrode Arrangement in an Air-Breathing Alkaline Direct Methanol Laminar Flow Fuel Cell. Journal of Power Sources 2012, 218, 28-33.

    • Tornow, C. E.; Thorson, M. R.; Ma, S.; Gewirth, A. A.; Kenis, P. J. A., Nitrogen-Based Catalysts for the Electrochemical Reduction of CO2 to CO. Journal of the American Chemical Society 2012, 134, (48), 19520-19523.

    • Thorson, M. R.; Goyal, S.; Gong, Y. C.; Zhang, G. G. Z.; Kenis, P. J. A., Microfluidic Approach to Polymorph Screening through Antisolvent Crystallization. Crystengcomm 2012, 14, (7), 2404-2412.

  • 2011
    • Thorson, M. R.; Goyal, S.; Schudel, B. R.; Zukoski, C. F.; Zhang, G. G. Z.; Gong, Y. C.; Kenis, P. J. A., A Microfluidic Platform for Pharmaceutical Salt Screening. Lab on a Chip 2011, 11, (22), 3829-3837.

    • Rosen, B. A.; Salehi-Khojin, A.; Thorson, M. R.; Zhu, W.; Whipple, D. T.; Kenis, P. J. A.; Masel, R. I., Ionic Liquid-Mediated Selective Conversion of CO2 to CO at Low Overpotentials. Science 2011, 334, (6056), 643-644.

    • Schudel, B. R.; Tanyeri, M.; Mukherjee, A.; Schroeder, C. M.; Kenis, P. J. A., Multiplexed Detection of Nucleic Acids in a Combinatorial Screening Chip. Lab on a Chip 2011, 11, (11), 1916-1923.

    • He, Y.; Kapoor, A.; Cook, S.; Liu, S. B.; Xiang, Y.; Rao, C. V.; Kenis, P. J. A.; Wang, F., The Non-Receptor Tyrosine Kinase Lyn Controls Neutrophil Adhesion by Recruiting the CrkL-C3G Complex and Activating Rap1 at the Leading Edge. Journal of Cell Science 2011, 124, (13), 2153-2164.

    • Kolossov, V. L.; Spring, B. Q.; Clegg, R. M.; Henry, J. J.; Sokolowski, A.; Kenis, P. J. A.; Gaskins, H. R., Development of a High-Dynamic Range, GFP-Based FRET Probe Sensitive to Oxidative Microenvironments. Experimental Biology and Medicine 2011, 236, (6), 681-691.

    • Lin, C.; Kolossov, V. L.; Tsvid, G.; Trump, L.; Henry, J. J.; Henderson, J. L.; Rund, L. A.; Kenis, P. J. A.; Schook, L. B.; Gaskins, H. R.; Timp, G., Imaging in Real-Time with Fret the Redox Response of Tumorigenic Cells to Glutathione Perturbations in a Microscale Flow. Integrative Biology 2011, 3, (3), 208-217.

    • Mohan, R.; Schudel, B. R.; Desai, A. V.; Yearsley, J. D.; Apblett, C. A.; Kenis, P. J. A., Design Considerations for Elastomeric Normally Closed Microfluidic Valves. Sensors and Actuators B-Chemical 2011, 160, (1), 1216-1223.

    • Schudel, B. R.; Tanyeri, M.; Mukherjee, A.; Schroeder, C. M.; Kenis, P. J. A., Multiplexed detection of nucleic acids in a combinatorial screening chip. Lab on a Chip 2011, 11, (11), 1916-1923. 

    • Cole, M. C.; Desai, A. V.; Kenis, P. J. A., Two-layer multiplexed peristaltic pumps for high-density integrated microfluidics. Sensors and Actuators B-Chemical 2011, 151, (2), 384-393

    • Lin, C.; Kolossov, V. L.; Tsvid, G.; Trump, L.; Henry, J. J.; Henderson, J. L.; Rund, L. A.; Kenis, P. J. A.; Schook, L. B.; Gaskins, H. R.; Timp, G., Imaging in real-time with FRET the redox response of tumorigenic cells to glutathione perturbations in a microscale flow. Integrative Biology 2011, 3, (3), 208-217.

    • Lin, C.; Kolossov, V. L.; Tsvid, G.; Trump, L.; Henry, J. J.; Henderson, J. L.; Rund, L. A.; Kenis, P. J. A.; Schook, L. B.; Gaskins, H. R.; Timp, G., Imaging in real-time with FRET the redox response of tumorigenic cells to glutathione perturbations in a microscale flow. Integrative Biology 2011, 3, (3), 208-217.

    • Lopez-Montesinos, P. O.; Yossakda, N.; Schmidt, A.; Brushett, F. R.; Pelton, W. E.; Kenis, P. J. A.,Design, fabrication, and characterization of a planar, silicon-based,monolithically integrated micro laminar flow fuel cell with a bridge-shaped microchannel cross-section. Journal of Power Sources 2011, 196, (10), 4638-4645.

    • Naughton, M. S.; Brushett, F. R.; Kenis, P. J. A., Carbonate resilience of flowing electrolyte-based alkaline fuel cells. Journal of Power Sources 2011, 196, (4), 1762-1768.

  • 2010
    • Perry, S. L.; Higdon, J. J. L.; Kenis, P. J. A., Design rules for pumping and metering of highly viscous fluids in microfluidics. Lab on a Chip 2010, 10, (22), 3112-3124. 

    • Kapoor, A.; Caporali, E. H. G.; Kenis, P. J. A.; Stewart, M. C., Microtopographically patterned surfaces promote the alignment of tenocytes and extracellular collagen. Acta Biomaterialia 2010, 6, (7), 2580-2589. 

    • Talreja, S.; Perry, S. L.; Guha, S.; Bhamidi, V.; Zukoski, C. F.; Kenis, P. J. A., Determination of the Phase Diagram for Soluble and Membrane Proteins. Journal of Physical Chemistry B 2010, 114, (13), 4432-4441.

    • Wang, Z. D.; Zhang, J. Q.; Ekman, J. M.; Kenis, P. J. A.; Lu, Y., DNA-Mediated Control of Metal Nanoparticle Shape: One-Pot Synthesis and Cellular Uptake of Highly Stable and Functional Gold Nanoflowers. Nano Letters 2010, 10, (5), 1886-1891.

    • Brushett, F. R.; Thorum, M. S.; Lioutas, N. S.; Naughton, M. S.; Tornow, C.; Jhong, H. R.; Gewirth, A. A.; Kenis, P. J. A., A Carbon-Supported Copper Complex of 3,5-Diamino-1,2,4-triazole as a Cathode Catalyst for Alkaline Fuel Cell Applications. Journal of the American Chemical Society 2010, 132, (35), 12185-12187. 

    • Wang, Z.; Zhang, J.; Ekman, J. M.; Kenis, P. J. A.; Lu, Y., DNA-Mediated Control of Metal Nanoparticle Shape: One-Pot Synthesis and Cellular Uptake of Highly Stable and Functional Gold Nanoflowers. Nano Letters 2010, 10, 1886-1891. 

    • Wheeler, T. D.; Zeng, D. X.; Desai, A. V.; Onal, B.; Reichert, D. E.; Kenis, P. J. A., Microfluidic labeling of biomolecules with radiometals for use in nuclear medicine. Lab on a Chip 2010, 10, (24), 3387-3396. 

    • Whipple, D. T.; Finke, E. C.; Kenis, P. J. A., Microfluidic Reactor for the Electrochemical Reduction of Carbon Dioxide: The Effect of pH. Electrochemical and Solid State Letters 2010, 13, (9), D109-D111. 

    • Whipple, D. T.; Kenis, P. J. A., Prospects of CO2 Utilization via Direct Heterogeneous Electrochemical Reduction. Journal of Physical Chemistry Letters 2010, 1, (24), 3451-3458. 

    • Brushett, F. R.; Duong, H. T.; Ng, J. W. D.; Behrens, R. L.; Wieckowski, A.; Kenis, P. J. A., Investigation of Pt, Pt3Co, and Pt3Co/Mo Cathodes for the ORR in a Microfluidic H-2/O-2 Fuel Cell. Journal of the Electrochemical Society 2010, 157, (6), B837-B845.

    • Goh, L.; Chen, K. J.; Bhamidi, V.; He, G. W.; Kee, N. C. S.; Kenis, P. J. A.; Zukoski, C. F.; Braatz, R. D., A Stochastic Model for Nucleation Kinetics Determination in Droplet-Based Microfluidic Systems. Crystal Growth & Design 2010, 10, (6), 2515-2521.

    • Hollinger, A. S.; Maloney, R. J.; Jayashree, R. S.; Natarajan, D.; Markoski, L. J.; Kenis, P. J. A., Nanoporous separator and low fuel concentration to minimize crossover in direct methanol laminar flow fuel cells. Journal of Power Sources 2010, 195, (11), 3523-3528.

    • Jayashree, R. S.; Yoon, S. K.; Brushett, F. R.; Lopez-Montesinos, P. O.; Natarajan, D.; Markoski, L. J.; Kenis, P. J. A., On the performance of membraneless laminar flow-based fuel cells. Journal of Power Sources 2010, 195, (11), 3569-3578.

  • 2009
    • Silvestre, J.; Kenis, P. J. A.; Leckband, D. E., Cadherin and Integrin Regulation of Epithelial Cell Migration. Langmuir 2009, 25, (17), 10092-10099.

    • Brushett, F. R.; Jayashree, R. S.; Zhou, W. P.; Kenis, P. J. A., Investigation of fuel and media flexible laminar low-based fuel cells. Electrochimica Acta 2009, 54, (27), 7099-7105.

    • Brushett, F. R.; Zhou, W. P.; Jayashree, R. S.; Kenis, P. J. A., Alkaline Microfluidic Hydrogen-Oxygen Fuel Cell as a Cathode Characterization Platform. Journal of the Electrochemical Society 2009, 156, (5), B565-B571.

    • Cole, M. C.; Kenis, P. J. A., Multiplexed electrical sensor arrays in microfluidic networks. Sensors and Actuators B-Chemical 2009, 136, (2), 350-358.

    • Gupta, C.; Shannon, M. A.; Kenis, P. J. A., Electronic Properties of a Monolayer-Electrolyte Interface Obtained from Mechanistic Impedance Analysis. Journal of Physical Chemistry C 2009, 113, (21), 9375-9391.

    • Gupta, C.; Shannon, M. A.; Kenis, P. J. A., Mechanisms of Charge Transport through Monolayer-Modified Polycrystalline Gold Electrodes in the Absence of Redox-Active Moieties. Journal of Physical Chemistry C 2009, 113, (11), 4687-4705.

    • Kee, N. C. S.; Woo, X. Y.; Goh, L. M.; Rusli, E.; He, G.; Bhamidi, V.; Tan, R. B. H.; Kenis, P. J. A.; Zukoski, C. F.; Braatz, R. D., Design of Crystallization Processes from Laboratory Research and Development to the Manufacturing Scale, Part I. American Pharmaceutical Review 2009, 11, (6), 11-115.

    • Kee, N. C. S.; Woo, X. Y.; Goh, L. M.; Rusli, E.; He, G.; Bhamidi, V.; Tan, R. B. H.; Kenis, P. J. A.; Zukoski, C. F.; Braatz, R. D., Design of Crystallization Processes from Laboratory Research and Development to the Manufacturing Scale, Part II. American Pharmaceutical Review 2009, 11, (7), 66-74.

    • Perry, S. L.; Roberts, G. W.; Tice, J. D.; Gennis, R. B.; Kenis, P. J. A., Microfluidic Generation of Lipidic Mesophases for Membrane Protein Crystallization. Crystal Growth & Design 2009, 9, (6), 2566-2569.

    • Schudel, B. R.; Choi, C. J.; Cunningham, B. T.; Kenis, P. J. A., Microfluidic chip for combinatorial mixing and screening of assays. Lab on a Chip 2009, 9, (12), 1676-1680.

    • Whipple, D.; Jayashree, R. S.; Egas, D.; Alonso-Vante, N.; Kenis, P. J. A., Ruthenium cluster-like chalcogenide as a methanol tolerant cathode catalyst in air-breathing laminar flow fuel cells. Electrochimica Acta 2009, 54, 4384-4388.

  • 2008
    • Kolossov, V. L.; Spring, B. Q.; Sokolowski, A.; Conour, J. E.; Clegg, R. M.; Kenis, P. J. A.; Gaskins, H. R., Engineering redox-sensitive linkers for genetically encoded FRET-based biosensors. Experimental Biology and Medicine 2008, 233, (2), 238-248.

  • 2007
    • Perring, M.; Mitchell, M.; Kenis, P. J. A.; Bowden, N. B., Patterning by etching at the nanoscale (PENs) on Si(111) through the controlled etching of PDMS. Chemistry of Materials 2007, 19, (11), 2903-2909.

    • Spendelow, J. S.; Xu, Q.; Goodpaster, J. D.; Kenis, P. J. A.; Wieckowski, A., The role of surface defects in CO oxidation, methanol oxidation, and oxygen reduction on pt(111). Journal of the Electrochemical Society 2007, 154, (12), F238-F242.

    • Gupta, C.; Mensing, G. A.; Shannon, M. A.; Kenis, P. J. A., Double transfer printing of small volumes of liquids. Langmuir 2007, 23, (5), 2906-2914.

    • Toepke, M. W.; Brewer, S. H.; Vu, D. M.; Rector, K. D.; Morgan, J. E.; Gennis, R. B.; Kenis, P. J. A.; Dyer, R. B., Microfluidic flow-flash: Method for investigating protein dynamics. Analytical Chemistry 2007, 79, (1), 122-128.

    • Talreja, S.; Kenis, P. J. A.; Zukoski, C. F., A kinetic model to simulate protein crystal growth in an evaporation-based crystallization platform. Langmuir 2007, 23, (8), 4516-4522.

    • Christian; Kenis, P. J., Fabrication of ceramic microscale structures. Journal of the American Ceramic Society 2007, 90, (9), 2779-2783.

    • He, G.; Tan, R. B. H.; Kenis, P. J. A.; Zukoski, C. F., Metastable states of small-molecule solutions. Journal of Physical Chemistry B 2007, 111, (51), 14121-14129.

    • He, G. W.; Tan, R. B. H.; Kenis, P. J. A.; Zukoski, C. F., Generalized phase Behavior of small molecules and nanoparticles. Journal of Physical Chemistry B 2007, 111, (43), 12494-12499.

    • Jayashree, R. S.; Mitchell, M.; Natarajan, D.; Markoski, L. J.; Kenis, P. J. A., Microfluidic hydrogen fuel cell with a liquid electrolyte. Langmuir 2007, 23, (13), 6871-6874.

  • 2006
    • Spendelow, J. S.; Goodpaster, J. D.; Kenis, P. J. A.; Wieckowski, A., Methanol dehydrogenation and oxidation on Pt(111) in alkaline solutions. Langmuir 2006, 22, (25), 10457-10464.

    • Christian; Mitchell, M.; Kenis, P. J. A., Ceramic microreactors for on-site hydrogen production from high temperature steam reforming of propane. Lab on a Chip 2006, 6, (10), 1328-1337.

    • Christian; Mitchell, M.; Kim, D. P.; Kenis, P. J. A., Ceramic microreactors for on-site hydrogen production. Journal of Catalysis 2006, 241, (2), 235-242.

    • Dutta, S.; Perring, M.; Barrett, S.; Mitchell, M.; Kenis, P. J. A.; Bowden, N. B., Cross metathesis on olefin-terminated monolayers on Si(111) using the Grubbs' catalyst. Langmuir 2006, 22, (5), 2146-2155.

    • He, G. W.; Bhamidi, V.; Wilson, S. R.; Tan, R. B. H.; Kenis, P. J. A.; Zukoski, C. F., Direct growth of gamma-glycine from neutral aqueous solutions by slow, evaporation-driven crystallization. Crystal Growth & Design 2006, 6, (8), 1746-1749.

    • Yoon, S. K.; Fichtl, G. W.; Kenis, P. J. A., Active control of the depletion boundary layers in microfluidic electrochemical reactors. Lab on a Chip 2006, 6, (12), 1516-1524.

    • Yeom, J.; Jayashree, R. S.; Rastogi, C.; Shannon, M. A.; Kenis, P. J. A., Passive direct formic acid microfabricated fuel cells. Journal of Power Sources 2006, 160, (2), 1058-1064.

  • 2004
    • Choban, E.R., Markoski, L.J., Wieckowski, A., and Kenis, P.J.A. (2004), "Micro-Fluidic Fuel Cell Based on Laminar Flow," Journal of Power Sources, 128, pp. 54-60.

    • Spendelow, J.S., Lu, G.Q., Kenis, P.J.A., and Wieckowski, A. (2004), "Electrooxidation of Adsorbed CO on Pt(111) and Pt(111)/Ru in Alkaline Media and Comparison with Results from Acidic Media," Journal of Electroanalytical Chemistry, in press.

  • 2003
    • Fuerstman, M.J. Deschatelets, P., Kane, R., Schwartz, A., Kenis, P.J.A., Deutch, J.M., and Whitesides, G.M. (2003), "Solving Mazes Using Microfluidic Networks," Langmuir, 19, pp. 4714-4722.

  • 2001
    • Ismagilov, R.F., Ng, J.M.K., Kenis, P.J.A., and Whitesides, G.M. (2001), "Microfluidic Arrays of Fluid-fluid Diffusional Contacts as Detection Elements and Combinatorial Tools," Analytical Chemistry, 73, pp. 5207-5213.

    • Ismagilov, R.F., Rosemarin, D., Kenis, P.J.A., Chiu, D.T., Zhang, W., Stone, H.A., and Whitesides, G.M. (2001), "Pressure-driven Laminar Flow in Tangential Microchannels: An Elastomeric Microfluidic Switch," Analytical Chemistry, 73, pp. 4682-4687.

  • 2000
    • Kenis, P.J.A., Ismagilov, R.F., Takayama, S., Whitesides, G.M., Li, S., and White, H.S. (2000), "Microfabrication Inside Capillaries Using Fluid Flow," Accounts of Chemical Research, 33, pp. 841-847.

Press

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  • a short bio including information on your educational background and your field
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