Directory

Yun-Sheng Chen's directory photo.

Yun-Sheng Chen

Assistant Professor

Primary Affiliation

Extracellular Vesicle Imaging and Therapy

Affiliations

Status Full-time Faculty

Home Department of Electrical and Computer Engineering

Phone

Email yunsheng@illinois.edu

Address 4255 Beckman Institute, 405 North Mathews Avenue

  • Biography

    Yun-Sheng Chen is an assistant professor in the Department of Electrical and Computer Engineering. He is affiliated with the Department of Electrical and Computer Engineering, Carle Illinois College of Medicine, Beckman Institute, and the Department of Bioengineering. Following his Ph.D., Yun-Sheng finished his postdoctoral training in the Molecular Imaging Program at Stanford University, Department of Radiology, working with Prof. Sanjiv Sam Gambhir.

    Education

    • M.A., materials science and engineering, National Sun-YAT Sen University 
    • M.A., optics, CREOL at the University of Florida
    • Ph.D., electrical engineering, University of Texas at Austin
  • Honors
    • 2020: JumpARCHES fund 
    • 2020: Google Faculty Research Award 
  • Research

    Research interests:

    • Electronics, Plasmonics, and Photonics

    • Medical imaging

    • Nanomedicine and bio-nanotechnology

    Research areas:

    • Biomedical Imaging, Bioengineering, and Acoustics

    • Nanotechnology

    Yun-Sheng Chen’s research develops new translatable imaging and diagnostic techniques using the photoacoustic effect.

  • 2024

    • Biomimetic-Membrane-Protected Plasmonic Nanostructures as Dual-Modality Contrast Agents for Correlated Surface-Enhanced Raman Scattering and Photoacoustic Detection of Hidden Tumor Lesions Srivastava, I., Xue, R., Huang, H. K., Wang, Z., Jones, J., Vasquez, I., Pandit, S., Lin, L., Zhao, S., Flatt, K., Gruev, V., Chen, Y. S. and Nie, S., Feb 21 2024, In: ACS Applied Materials and Interfaces. 16, 7, p. 8554-8569 16 p.

    2023

    • Automatically Reconfigurable Metasurface for Free-Positioning Wireless Power Transfer Ye, X., Wang, H., Yu, J., Chen, Y. S. and Zhao, Y., 2023, 2023 IEEE Wireless Power Technology Conference and Expo, WPTCE 2023 - Proceedings. Institute of Electrical and Electronics Engineers Inc., (2023 IEEE Wireless Power Technology Conference and Expo, WPTCE 2023 - Proceedings).
    • Hybrid photoacoustic and fast super-resolution ultrasound imaging Zhao, S., Hartanto, J., Joseph, R., Wu, C. H., Zhao, Y. and Chen, Y. S., Dec 2023, In: Nature communications. 14, 1, 2191.
    • Magnetic Nearfield Reshaping Metasurfaces Wang, H., Ye, X., Yu, J., Chen, Y. S. and Zhao, Y., 2023, In: International Conference on Metamaterials, Photonic Crystals and Plasmonics. p. 355-356 2 p.
    • Photoacoustic signal enhancement in dual-contrast gastrin-releasing peptide receptor-targeted nanobubbles Zhao, S., Lee, L., Zhao, Y., Liang, N. C. and Chen, Y. S., Jan 17 2023, In: Frontiers in Bioengineering and Biotechnology. 11, 1102651.
    • Qi Standard Compatible Metasurface for Multi-Device Wireless Power Transfer with Tunable Power Division Yu, J., Wang, H., Ye, X., Chen, Y. S. and Zhao, Y., 2023, 2023 IEEE Wireless Power Technology Conference and Expo, WPTCE 2023 - Proceedings. Institute of Electrical and Electronics Engineers Inc., (2023 IEEE Wireless Power Technology Conference and Expo, WPTCE 2023 - Proceedings).
    • Visualizing ultrafast photothermal dynamics with decoupled optical force nanoscopy Wang, H., Meyer, S. M., Murphy, C. J., Chen, Y. S. and Zhao, Y., Dec 2023, In: Nature communications. 14, 1, 7267.

    2022

    • Understanding the near-field photoacoustic spatiotemporal profile from nanostructures Wang, H., Chen, Y. S. and Zhao, Y., Dec 2022, In: Photoacoustics. 28, 100425.

    2021

    • A wearable metasurface for high efficiency, free-positioning omnidirectional wireless power transfer Wang, H., Chen, Y. S. and Zhao, Y., Dec 2021, In: New Journal of Physics. 23, 12, 125003.
    • Mitochondrial copper depletion suppresses triple-negative breast cancer in mice Cui, L., Gouw, A. M., LaGory, E. L., Guo, S., Attarwala, N., Tang, Y., Qi, J., Chen, Y.-S., Gao, Z., Casey, K. M., Bazhin, A. A., Chen, M., Hu, L., Xie, J., Fang, M., Zhang, C., Zhu, Q., Wang, Z., Giaccia, A. J. and Gambhir, S. S. and 6 others, , Mar 2021, In: Nature Biotechnology. 39, 3, p. 357-367 11 p.
    • On-demand field shaping for enhanced magnetic resonance imaging using an ultrathin reconfigurable metasurface Wang, H., Huang, H. K., Chen, Y. S. and Zhao, Y., Jun 2021, In: VIEW. 2, 3, 20200099.
    • Quantifying molecular- To cellular-level forces in living cells Pan, J., Kmieciak, T., Liu, Y. T., Wildenradt, M., Chen, Y. S. and Zhao, Y., Dec 2 2021, In: Journal of Physics D: Applied Physics. 54, 48, 483001.
    • Ultra-high-frequency radio-frequency acoustic molecular imaging with saline nanodroplets in living subjects Chen, Y. S., Zhao, Y., Beinat, C., Zlitni, A., Hsu, E. C., Chen, D. H., Achterberg, F., Wang, H., Stoyanova, T., Dionne, J. and Gambhir, S. S., Jun 2021, In: Nature Nanotechnology. 16, 6, p. 717-724 8 p.

    2020

    • Carbon-coated FeCo nanoparticles as sensitive magnetic-particle-imaging tracers with photothermal and magnetothermal properties Song, G., Kenney, M., Chen, Y. S., Zheng, X., Deng, Y., Chen, Z., Wang, S. X., Gambhir, S. S., Dai, H. and Rao, J., Mar 2020, In: Nature biomedical engineering. 4, 3, p. 325-334 10 p.
    • Trop2 is a driver of metastatic prostate cancer with neuroendocrine phenotype via PARP1 Hsu, E. C., Rice, M. A., Bermudez, A., Marques, F. J. G., Aslan, M., Liu, S., Ghoochani, A., Zhang, C. A., Chen, Y. S., Zlitni, A., Kumar, S., Nolley, R., Habte, F., Shen, M., Koul, K., Peehl, D. M., Zoubeidi, A., Gambhir, S. S., Kunder, C. A. and Pitteri, S. J. and 2 others, , Jan 28 2020, In: Proceedings of the National Academy of Sciences of the United States of America. 117, 4, p. 2032-2042 11 p.

    2019

    • Miniature gold nanorods for photoacoustic molecular imaging in the second near-infrared optical window Chen, Y. S., Zhao, Y., Yoon, S. J., Gambhir, S. S. and Emelianov, S., May 1 2019, In: Nature Nanotechnology. 14, 5, p. 465-472 8 p.
    • Optical force microscopy: Combining light with atomic force microscopy for nanomaterial identification Jahan, N., Wang, H., Zhao, S., Dutta, A., Huang, H. K., Zhao, Y. and Chen, Y. S., Oct 1 2019, In: Nanophotonics. 8, 10, p. 1659-1671 13 p.

    2018

    • The Utility of [18F]DASA-23 for Molecular Imaging of Prostate Cancer with Positron Emission Tomography Beinat, C., Haywood, T., Chen, Y. S., Patel, C. B., Alam, I. S., Murty, S. and Gambhir, S. S., Dec 1 2018, In: Molecular Imaging and Biology. 20, 6, p. 1015-1024 10 p.

    2017

    • Dynamic contrast-enhanced photoacoustic imaging using photothermal stimuli-responsive composite nanomodulators Chen, Y. S., Yoon, S. J., Frey, W., Dockery, M. and Emelianov, S., Jun 8 2017, In: Nature communications. 8, 15782.

    2014

    • Intravascular photoacoustics for image-guidance and temperature monitoring during plasmonic photothermal therapy of atherosclerotic plaques: A feasibility study Yeager, D., Chen, Y. S., Litovsky, S. and Emelianov, S., Feb 28 2014, In: Theranostics. 4, 1, p. 36-46 11 p.
    • In-Vivo ultrasound and photoacoustic image-guided photothermal cancer therapy using silica-coated gold nanorods Kim, S., Chen, Y. S., Luke, G. and Emelianov, S., May 2014, In: IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control. 61, 5, p. 891-897 7 p., 6805702.
    • Photoacoustic and ultrasound imaging using dual contrast perfluorocarbon nanodroplets triggered by laser pulses at 1064 nm Hannah, A. S., VanderLaan, D., Chen, Y. S. and Emelianov, S. Y., Sep 1 2014, In: Biomedical Optics Express. 5, 9, p. 3042-3052 11 p., A3042.
    • Photoacoustic Imaging for Cancer Diagnosis and Therapy Guidance Chen, Y. S., Yeager, D. & Emelianov, S. Y., Mar 2014, Cancer Theranostics. Chen, X. and Wong, S. (eds.). Elsevier Inc., p. 139-158 20 p.

    2013

    • Development and optimization of near-IR contrast agents for immune cell tracking Joshi, P. P., Yoon, S. J., Chen, Y. S., Emelianov, S. and Sokolov, K. V., Nov 1 2013, In: Biomedical Optics Express. 4, 11, p. 2609-2618 10 p.
    • Modulation of photoacoustic signal generation from metallic surfaces Mitcham, T., Homan, K., Frey, W., Chen, Y. S., Emelianov, S., Hazle, J. and Bouchard, R., May 2013, In: Journal of biomedical optics. 18, 5, 056008.
    • Photoacoustic signal amplification through plasmonic nanoparticle aggregation Bayer, C. L., Nam, S. Y., Chen, Y. S. and Emelianov, S. Y., 2013, In: Journal of biomedical optics. 18, 1, 016001.
    • Sensitivity enhanced nanothermal sensors for photoacoustic temperature mapping Chen, Y. S., Frey, W., Walker, C., Aglyamov, S. and Emelianov, S., Jun 2013, In: Journal of Biophotonics. 6, 6-7, p. 534-542 9 p.
    • Silica-coated gold nanoplates as stable photoacoustic contrast agents for sentinel lymph node imaging Luke, G. P., Bashyam, A., Homan, K. A., Makhija, S., Chen, Y. S. and Emelianov, S. Y., Nov 15 2013, In: Nanotechnology. 24, 45, 455101.

    2012

    • Environment-dependent generation of photoacoustic waves from plasmonic nanoparticles Chen, Y. S., Frey, W., Aglyamov, S. and Emelianov, S., Jan 9 2012, In: Small. 8, 1, p. 47-52 6 p.
    • Feasibility of contrast-enhanced photoacoustic liver imaging at a wavelength of 1064 nm Chen, Y. S., Homan, K., Xu, D., Frey, W. and Emelianov, S., 2012, Biomedical Optics, BIOMED 2012. Optical Society of America (OSA), p. BM2B.7 (Biomedical Optics, BIOMED 2012).

    2011

    • In vivo three-dimensional spectroscopic photoacoustic imaging for monitoring nanoparticle delivery Kim, S., Chen, Y. S., Luke, G. P. and Emelianov, S. Y., Sep 1 2011, In: Biomedical Optics Express. 2, 9, p. 2540-2550 11 p.
    • Magneto-photo-acoustic imaging Qu, M., Mallidi, S., Mehrmohammadi, M., Truby, R., Homan, K., Joshi, P., Chen, Y. S., Sokolov, K. and Emelianov, S., Feb 1 2011, In: Biomedical Optics Express. 2, 2, p. 385-396 12 p.
    • Multiplex photoacoustic molecular imaging using targeted silica-coated gold nanorods Bayer, C. L., Chen, Y. S., Kim, S., Mallidi, S., Sokolov, K. and Emelianov, S., 2011, In: Biomedical Optics Express. 2, 7, p. 1828-1835 8 p.
    • Multiplex photoacoustic molecular imaging using targeted silica-coated gold nanorods Bayer, C. L., Chen, Y. S., Kim, S., Mallidi, S., Sokolov, K. and Emelianov, S., 2011, In: Biomedical Optics Express. 2, 7, p. 1828-1835 8 p.
    • Photoacoustic imaging to guide needle injections Su, J. L., Karpiouk, A. B., Chen, Y. S. and Emelianov, S. Y., 2011, Photons Plus Ultrasound: Imaging and Sensing 2011. 78993A. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; vol. 7899).
    • Silica-coated gold nanorods as photoacoustic signal nanoamplifiers Chen, Y. S., Frey, W., Kim, S., Kruizinga, P., Homan, K. and Emelianov, S., Feb 9 2011, In: Nano letters. 11, 2, p. 348-354 7 p.

    2010

    • Advances in clinical and biomedical applications of photoacoustic imaging Su, J. L., Wang, B., Wilson, K. E., Bayer, C. L., Chen, Y. S., Kim, S., Homan, K. A. and Emelianov, S. Y., Nov 2010, In: Expert Opinion on Medical Diagnostics. 4, 6, p. 497-510 14 p.
    • Combined photoacoustic and magneto-motive ultrasound imaging Qu, M., Kim, S., Mehrmohammadi, M., Mallidi, S., Joshi, P., Homan, K., Chen, Y. S. and Emelianov, S., 2010, Photons Plus Ultrasound: Imaging and Sensing 2010. 756433. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; vol. 7564).
    • Combined photothermal therapy and magneto-motive ultrasound imaging using multifunctional nanoparticles Mehrmohammadi, M., Ma, L. L., Chen, Y. S., Qu, M., Joshi, P., Chen, R. M., Johnston, K. P. and Emelianov, S., 2010, Nanoscale Imaging, Sensing, and Actuation for Biomedical Applications VII. 757405. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; vol. 7574).
    • Enhanced thermal stability of silica-coated gold nanorods for photoacoustic imaging and image-guided therapy Chen, Y. S., Frey, W., Kim, S., Homan, K., Kruizinga, P., Sokolov, K. and Emelianov, S., Apr 26 2010, In: Optics Express. 18, 9, p. 8867-8877 11 p.
    • Molecular diagnosis of cancer using multiplex photoacoustic imaging with targeted nanorods Bayer, C. L., Chen, Y. S., Kim, S., Mallidi, S., Sokolov, K. and Emelianov, S., 2010, 2010 IEEE International Ultrasonics Symposium, IUS 2010. p. 503-506 4 p. 5935741. (Proceedings - IEEE Ultrasonics Symposium).
    • On stability of molecular therapeutic agents for noninvasive photoacoustic and ultrasound image-guided photothermal therapy Chen, Y. S., Kruizinga, P., Joshi, P. P., Kim, S., Homan, K., Sokolov, K., Frey, W. and Emelianov, S., 2010, Photons Plus Ultrasound: Imaging and Sensing 2010. 75641Q. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; vol. 7564).
    • Prospects of molecular photoacoustic imaging at 1064 nm wavelength Homan, K., Kim, S., Chen, Y. S., Wang, B., Mallidi, S. and Emelianov, S., Aug 1 2010, In: Optics Letters. 35, 15, p. 2663-2665 3 p.
    • Ultrasound and photoacoustic image-guided photothermal therapy using silica-coated gold nanorods: In-vivo study Kim, S., Chen, Y. S., Luke, G. P., Mehrmohammadi, M., Cook, J. R. and Emelianov, S. Y., 2010, 2010 IEEE International Ultrasonics Symposium, IUS 2010. p. 233-236 4 p. 5935601. (Proceedings - IEEE Ultrasonics Symposium).

    2009

    • Capacitor-embedded 0.54 pJ/bit silicon-slot photonic crystal waveguide modulator Chen, X., Chen, Y. S., Zhao, Y., Jiang, W. and Chen, R. T., Mar 1 2009, In: Optics Letters. 34, 5, p. 602-604 3 p.
    • Delay-time-enhanced flat-band photonic crystal waveguides with capsule-shaped holes on silicon nanomembrane Chen, Y. S., Zhao, Y., Hosseini, A., Kwong, D., Jiang, W., Bank, S. R., Tutuc, E. and Chen, R. T., Sep 2009, In: IEEE Journal on Selected Topics in Quantum Electronics. 15, 5, p. 1510-1514 5 p., 5256334.
    • Modified slab photonic crystal structure for delay time enhancement using capsule shaped holes Chen, Y. S., Hosseini, A., Kwong, D., Zhao, Y., Subbaraman, H. and Chen, R. T., 2009, 2009 14th OptoElectronics and Communications Conference, OECC 2009. 5222077. (2009 14th OptoElectronics and Communications Conference, OECC 2009).
    • Molecular therapeutic agents for noninvasive photoacoustic image-guided photothermal therapy Joshi, P. P., Chen, Y. S., Kim, S., Shah, J., Sokolov, K. and Emelianov, S., 2009, Proceedings of the 31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society: Engineering the Future of Biomedicine, EMBC 2009. IEEE Computer Society, p. 4106-4109 4 p. 5334025. (Proceedings of the 31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society: Engineering the Future of Biomedicine, EMBC 2009).
    • Silicon nano-membranes for efficient large angle optical beam steering Hosseini, A., Zhao, Y., Chen, Y. S., Kwong, D. N. and Chen, R. T., 2009, 2nd IEEE LEOS Winter Topicals, WTM 2009. p. 104-105 2 p. 4771678. (2nd IEEE LEOS Winter Topicals, WTM 2009).
    • Ultrasound-based imaging of nanoparticles: From molecular and cellular imaging to therapy guidance Mallidi, S., Wang, B., Mehrmohammadi, M., Qu, M., Chen, Y. S., Joshi, P., Kim, S., Homan, K. A., Karpiouk, A. B., Smalling, R. W., Sokolov, K. and Emelianov, S. Y., 2009, 2009 IEEE International Ultrasonics Symposium and Short Courses, IUS 2009. 5441484. (Proceedings - IEEE Ultrasonics Symposium).
    • Unequally spaced waveguide arrays for silicon nanomembrane-based efficient large angle optical beam steering Hosseini, A., Kwong, D., Zhao, Y., Chen, Y. S., Crnogorac, F., Pease, R. F. W. and Chen, R. T., Sep 2009, In: IEEE Journal on Selected Topics in Quantum Electronics. 15, 5, p. 1439-1446 8 p., 5175336.

    2008

    • Metallo-dielectric nanophotonic materials via direct laser writing and electroless metallization Kuebler, S. M., Chen, Y. S. and Tal, A., 2008, Advanced Fabrication Technologies for Micro/Nano Optics and Photonics. 68830L. (Proceedings of SPIE - The International Society for Optical Engineering; vol. 6883).
    • Preparation of metallo-dielectric metamaterials by multi-photon direct laser writing Kuebler, S. M., Tal, A. and Chen, Y. S., 2008, Plasmonics and Metamaterials, META_PLAS 2008. Optical Society of America (OSA), (Optics InfoBase Conference Papers).
    • Preparation of metallo-dielectric photonic crystals by multi-photon direct laser writing Kuebler, S. M., Tal, A. and Chen, Y. S., 2008, Photonic Crystal Materials and Devices VII. 69010Z. (Proceedings of SPIE - The International Society for Optical Engineering; vol. 6901).

    2007

    • Fabrication and characterization of three-dimensional copper metallodielectric photonic crystals Tal, A., Chen, Y. S., Williams, H. E., Rumpf, R. C. and Kuebler, S. M., Dec 24 2007, In: Optics Express. 15, 26, p. 18283-18293 11 p.
    • Route to three-dimensional metallized microstructures using cross-linkable epoxide SU-8 Chen, Y. S., Tal, A. and Kuebler, S. M., Aug 7 2007, In: Chemistry of Materials. 19, 16, p. 3858-3860 3 p.
    • Silvered three-dimensional polymeric photonic crystals having a large mid-infrared stop band Kuebler, S. M., Tal, A. and Chen, Y. S., 2007, Micromachining Technology for Micro-Optics and Nano-Optics V and Microfabrication Process Technology XII. 646213. (Proceedings of SPIE - The International Society for Optical Engineering; vol. 6462).

    2006

    • Fabrication and characterization of three-dimensional silver-coated polymeric microstructures Chen, Y. S., Tal, A., Torrance, D. B. and Kuebler, S. M., Sep 5 2006, In: Advanced Functional Materials. 16, 13, p. 1739-1744 6 p.