Status Affiliate Faculty
Home Department of Mechanical Science and Engineering
Phone 333-8552
Email saif@illinois.edu
Address
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Biography
Taher Saif is a professor in the Department of Mechanical Science and Engineering. His primary affiliation is Neurotechnology for Memory and Cognition.
Education
B.S., civil engineering, Bangladesh University of Engineering and Technology, 1984
M.S., civil engineering, Washington State University, 1987
Ph.D., theoretical & applied mechanics, Cornell University, 1993
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Honors
2020: Engineering Science Medal, Society of Engineering Science
2018: Warner T. Koiter Medal, American Society of Mechanical Engineers
2016: Member, International Advisory Board, North South University, Dhaka, Bangladesh, 2016-
2012-2016: Member, Board of Directors, Society of Engineering Science
2016: President, Society of Engineering Science
2009: College of Engineering Outstanding Advisors list
2006: MechSE Alumni Effective Teaching Award
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Research
Research areas:
Applied Physics
Chemistry
Health and Bio
Research interests:
Biohybrid robots, engineered living systems
Biomechanics: cellular mechanics and mechanotransduction, cancer metastasis, neuro mechanics
Deformation mechanisms of nanoscale materials
Mechanics of micro-electro mechanical systems (MEMS)
Professor Saif's research focuses on the mechanics of nanoscale materials and living cells. He uses both theory and experiment to explore (1) the effect of size on the mechanics of materials, and (2) the role of mechanical force in determining the functionality of cells and cell clusters.
Professor Saif demonstrated experimentally, for the first time, that plastic deformation in nanocrystalline metal films can be reversible. After plastic deformation, metals with grain sizes between 50 and 100 nanometers recover most of their plastic strain under macroscopically stress-free condition. This recovery is time dependent and thermally activated. Saif showed that the recovery originates from the small size and heterogeniety of microstructure of the metal specimens. The research, which was reported in Science, raises the possibility of manufacturing metal components that can heal themselves after being deformed or dented.
In the area of cellular mechanics, Professor Saif's projects involve neurons, cancer and cardiac cells, and interactions between cells in clusters. He seeks to address questions such as: What is the role of tension in neurons on memory and learning? Does mechanical microenvironment influence the onset of metastasis during cancer development? Can clusters of cells be guided so that they evolve into biological machines? He, together with Professor Akira Chiba of the the University of Maimi, showed that neurons are under mechanical tension, and that such tension might be essential for memory and learning.
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2013
- Cha, C. Y.; Antoniadou, E.; Lee, M.; Jeong, J. H.; Ahmed, W. W.; Saif, T. A.; Boppart, S. A.; Kong, H., Tailoring Hydrogel Adhesion to Polydimethylsiloxane Substrates Using Polysaccharide Glue. Angewandte Chemie-International Edition 2013, 52, (27), 6949-6952, DOI: 10.1002/anie.201302925
2012
- Ahmed, W. W.; Li, T. C.; Rubakhin, S. S.; Chiba, A.; Sweedler, J. V.; Saif, T. A., Mechanical Tension Modulates Local and Global Vesicle Dynamics in Neurons. Cellular and Molecular Bioengineering 2012, 5, (2), 155-164.
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2023
2022
2021
2020
2019
- Illinois team develops first-of-its-kind in-vitro 3D neural tissue model
- Researchers build microscopic biohybrid robots propelled by muscles, nerves
- Beckman researchers to receive $400k to explore how exercise may aid cognition
- 9 projects with Beckman researchers receive funding from the Cancer Center
2014