Directory

Issam Moussa's directory photo.

Issam Moussa

Professor

Primary Affiliation

Cognition, Lifespan Engagement, Aging, and Resilience

Affiliations

Status Affiliate Faculty

Home Clinical Sciences

Phone

Email imoussa@illinois.edu

Address 1215-H Beckman Institute, 405 North Mathews Avenue

  • Biography

    Issam D. Moussa is a professor in the Carle Illinois College of Medicine - Administration and Department of Bioengineering. Issam D. Moussa is the medical director of the Carle Heart & Vascular Institute as well as a clinical professor of medicine and the interim department head of clinical sciences at the Carle Illinois College of Medicine. Currently, Dr. Moussa's research priorities are focused on the brain-heart axis with particular emphasis on translational and clinical applications. His additional affiliations include the associate dean for Research of Carle Illinois College of Medicine and institute affiliate for Beckman Institute for Advanced Science and Technology.

    Education

    MD., Damascus University Medical School in Syria

    MBA., health administration, University of Colorado

  • Research

    Research Areas:

    • Neurocardiology

    • Artificial Intelligence in Healthcare

    • Cardiovascular Devices

    Research Interests:

    • Brain-heart axis

    • Translational and clinical applications

    Significant progress has been made in understanding the structure and function of the brain and the heart as separate organs. Emerging experimental evidence, however, points to the presence of a heart-brain axis that operates in intimate coordination in health and disease. Significant gaps remain in deciphering the exact mechanisms of heart-brain interaction and its impact in humans. Professor Moussa’s neuro-cardiology research group aims to discover the novel mechanisms governing those interactions and translate these findings to impactful diagnostic and therapeutic advances.

  • 2023

    • Kurpad, K. P., Haider, M. Z., Garg, N., Katamreddy, A., Adoni, N., Moussa, I. D., & Mehta, S. S. (2023). Is Concomitant Mitral Stenosis Associated With Worse Outcomes in Patients Who Underwent TAVR? Insights from a National Database. American Journal of Cardiology, 209, 85-88. https://doi.org/10.1016/j.amjcard.2023.09.076
    • Kurpad, K. P., Khalil, M. H., Katamreddy, A., Mehta, H., Adoni, N., Moussa, I. D., & Mehta, S. S. (2023). National Trends of Transcatheter Versus Surgical Aortic Valve Replacement With and Without Coronary Artery Bypass Graft. American Journal of Cardiology, 205, 94-96. https://doi.org/10.1016/j.amjcard.2023.06.065
    • Mori, S., Moussa, I. D., Hanna, P., & Shivkumar, K. (2023). Veiled Anatomy of the Tricuspid Valve Perimeter: What the Interventionalist Must Know…But Cannot See! JACC: Cardiovascular Interventions, 16(5), 614-616. https://doi.org/10.1016/j.jcin.2022.11.009
    • Moussa, I. (2023). Predicting Behavior of Device-Related Thrombus After Left Atrial Appendage Occlusion: The Heisenberg's Uncertainty Principle Applies. JACC: Cardiovascular Interventions, 16(22), 2733-2735. https://doi.org/10.1016/j.jcin.2023.10.030
    • Sato, T., Adlaka, K., Moussa, I. D., Hanna, P., Do, D. H., Fishbein, M. C., Shivkumar, K., & Mori, S. (2023). Understanding Cardiac Anatomy and Imaging to Improve Safety of Procedures: The Right Ventricle. JACC: Cardiovascular Imaging, 16(10), 1348-1352. https://doi.org/10.1016/j.jcmg.2023.06.026
    • Sato, T., Moussa, I. D., Hanna, P., Shivkumar, K., & Mori, S. (2023). Insights Into Interaction Between Clip Device and the Mitral Valve Apparatus in the Human Heart. JACC: Case Reports, 22, Article 101999. https://doi.org/10.1016/j.jaccas.2023.101999
    • Sato, T., Moussa, I. D., Hanna, P., Shivkumar, K., & Mori, S. (2023). Intermediate Accessory Papillary Muscle: An Anatomic Variant of Interest for Transcatheter Edge-to-Edge Mitral Valve Repair. Circulation: Cardiovascular Imaging, 16(10), E015151. https://doi.org/10.1161/CIRCIMAGING.122.015151
    • Saw, J., Holmes, D. R., Cavalcante, J. L., Freeman, J. V., Goldsweig, A. M., Kavinsky, C. J., Moussa, I. D., Munger, T. M., Price, M. J., Reisman, M., Sherwood, M. W., Turi, Z. G., Wang, D. D., & Whisenant, B. K. (2023). SCAI/HRS expert consensus statement on transcatheter left atrial appendage closure. Heart Rhythm, 20(5), e1-e16. https://doi.org/10.1016/j.hrthm.2023.01.007
    • Saw, J., Holmes, D. R., Cavalcante, J. L., Freeman, J. V., Goldsweig, A. M., Kavinsky, C. J., Moussa, I. D., Munger, T. M., Price, M. J., Reisman, M., Sherwood, M. W., Turi, Z. G., Wang, D. D., & Whisenant, B. K. (2023). SCAI/HRS Expert Consensus Statement on Transcatheter Left Atrial Appendage Closure. JACC: Cardiovascular Interventions, 16(11), 1384-1400. https://doi.org/10.1016/j.jcin.2023.01.011
    • Saw, J., Holmes, D. R., Cavalcante, J. L., Freeman, J. V., Goldsweig, A. M., Kavinsky, C. J., Moussa, I. D., Munger, T. M., Price, M. J., Reisman, M., Sherwood, M. W., Turi, Z. G., Wang, D. D., & Whisenant, B. K. (2023). SCAI/HRS Expert Consensus Statement on Transcatheter Left Atrial Appendage Closure. Journal of the Society for Cardiovascular Angiography and Interventions, 2(3), Article 100577. https://doi.org/10.1016/j.jscai.2022.100577
    • Shaffer, A., Nigh, N., Weisbaum, D., Anderson, A., Wszalek, T., Sutton, B. P., Webb, A., Damon, B., Moussa, I., & Arnold, P. M. (2023). Cardiothoracic and Vascular Surgery Implant Compatibility With Ultrahigh Field Magnetic Resonance Imaging (4.7 Tesla and 7 Tesla). American Journal of Cardiology, 201, 239-246. https://doi.org/10.1016/j.amjcard.2023.05.062

    2022

    • Anderson, H. V., Masri, S. C., Abdallah, M. S., Chang, A. M., Cohen, M. G., Elgendy, I. Y., Gulati, M., Lapoint, K., Madan, N., Moussa, I. D., Ramirez, J., Simon, A. W., Singh, V., Waldo, S. W., & Williams, M. S. (2022). 2022 ACC/AHA Key Data Elements and Definitions for Chest Pain and Acute Myocardial Infarction: A Report of the American Heart Association/American College of Cardiology Joint Committee on Clinical Data Standards. Circulation: Cardiovascular Quality and Outcomes, 15(10), E000112. https://doi.org/10.1161/HCQ.0000000000000112
    • Okuya, Y., & Moussa, I. D. (2022). Surgical bailout after transcatheter aortic valve replacement: Hospital procedural volume matters! Catheterization and Cardiovascular Interventions, 99(1), 169-170. https://doi.org/10.1002/ccd.30031
    • Okuya, Y., Gohil, K., & Moussa, I. D. (2022). Angiography versus FFR guided complete revascularization versus culprit-only revascularization for patients presenting with STEMI: Network meta-analysis. Catheterization and Cardiovascular Interventions, 100(3), 340-350. https://doi.org/10.1002/ccd.30304
    • Okuya, Y., Gohil, K., & Moussa, I. D. (2022). Impact of Left Ventricular Systolic Function After Moderate-to-Severe Isolated Traumatic Brain Injury: A Systematic Review and Meta-Analysis. Cardiology in Review, 30(6), 293-298. https://doi.org/10.1097/CRD.0000000000000403
    • SYMPLICITY HTN-3 Steering Committee Investigators (2022). Long-term outcomes after catheter-based renal artery denervation for resistant hypertension: final follow-up of the randomised SYMPLICITY HTN-3 Trial. The Lancet, 400(10361), 1405-1416. https://doi.org/10.1016/S0140-6736(22)01787-1
    • Writing Committee Members (2022). 2022 ACC/AHA Key Data Elements and Definitions for Chest Pain and Acute Myocardial Infarction: A Report of the American Heart Association/American College of Cardiology Joint Committee on Clinical Data Standards. Journal of the American College of Cardiology, 80(17), 1660-1700. https://doi.org/10.1016/j.jacc.2022.05.012

    2021

    • for the Myocardial Infarction Data Acquisition System (MIDAS 41) study group (2021). A Twenty-Year Analysis of Demographics, Surgical Management, and Outcomes of Aortic Stenosis in New Jersey. American Journal of Cardiology, 150, 82-88. https://doi.org/10.1016/j.amjcard.2021.03.046
    • Gupta, A., Huerta, E., Zhao, Z., & Moussa, I. (2021). Deep Learning for Cardiologist-Level Myocardial Infarction Detection in Electrocardiograms. In T. Jarm, A. Cvetkoska, S. Mahnic-Kalamiza, & D. Miklavcic (Eds.), 8th European Medical and Biological Engineering Conference - Proceedings of the EMBEC 2020 (pp. 341-355). (IFMBE Proceedings; Vol. 80). Springer. https://doi.org/10.1007/978-3-030-64610-3_40
    • Moussa, I. D. (2021). Prediction of left circumflex artery impingement after indirect mitral annuloplasty with the carillon device: “There is more to this than meets the eye!”. Catheterization and Cardiovascular Interventions, 98(7), 1402-1403. https://doi.org/10.1002/ccd.29986
    • Moussa, I. D., & Lee, R. J. (2021). Unraveling the Gordian Knot! Hospital Volume Threshold to Optimize Outcomes After Left Atrial Appendage Occlusion. JACC: Cardiovascular Interventions, 14(5), 562-565. https://doi.org/10.1016/j.jcin.2021.01.011
    • Okuya, Y., & Moussa, I. D. (2021). Coronary bypass graft surgery accentuates proximal coronary disease progression! Catheterization and Cardiovascular Interventions, 98(3), 492. https://doi.org/10.1002/ccd.29875
    • Okuya, Y., & Moussa, I. D. (2021). Hemolysis after transcatheter mitral valve replacement: An underreported phenomenon! Catheterization and Cardiovascular Interventions, 98(4), 786-787. https://doi.org/10.1002/ccd.29901
    • Okuya, Y., Park, J. Y., Garg, A., & Moussa, I. (2021). Coronary artery spasm during catheter ablation caused by the intravenous infusion of isoproterenol. Internal Medicine, 60(8), 1221-1224. https://doi.org/10.2169/internalmedicine.6130-20
    • Tamez, H., Secemsky, E. A., Valsdottir, L. R., Moussa, I. D., Song, Y., Simonton, C. A., Gibson, C. M., Popma, J. J., & Yeh, R. W. (2021). Long-term outcomes of percutaneous coronary intervention for in-stent restenosis among Medicare beneficiaries. EuroIntervention, 17(5), 380-387. https://doi.org/10.4244/EIJ-D-19-01031

    2020

    • Box, L. C., Blankenship, J. C., Henry, T. D., Messenger, J. C., Cigarroa, J. E., Moussa, I. D., Snyder, R. W., Duffy, P. L., Carr, J. G., Tukaye, D. N., Ang, L., Shah, B., Rao, S. V., & Mahmud, E. (2020). SCAI position statement on the performance of percutaneous coronary intervention in ambulatory surgical centers. Catheterization and Cardiovascular Interventions, 96(4), 862-870. https://doi.org/10.1002/ccd.28991
    • Majithia, A., Matheny, M. E., Dani, S. S., Paulus, J. K., Marinac-Dabic, D., Robbins, S., Ssemaganda, H., Hewitt, K., Ponirakis, A., Loyo-Berrios, N., Moussa, I., Drozda, J., Normand, S. L., & Resnic, F. S. (2020). Impact of early surveillance on safety signal identification in the CathPCI DELTA study. BMJ Surgery, Interventions, and Health Technologies, 2(1), Article e000047. https://doi.org/10.1136/bmjsit-2020-000047
    • Moussa, I. D., Mohananey, D., Saucedo, J., Stone, G. W., Yeh, R. W., Kennedy, K. F., Waksman, R., Teirstein, P., Moses, J. W., & Simonton, C. (2020). Trends and Outcomes of Restenosis After Coronary Stent Implantation in the United States. Journal of the American College of Cardiology, 76(13), 1521-1531. https://doi.org/10.1016/j.jacc.2020.08.002

    2019

    • Majithia, A., Matheny, M. E., Paulus, J. K., Marinac-Dabic, D., Robbins, S., Ssemaganda, H., Hewitt, K., Ponirakis, A., Loyo-Berrios, N., Moussa, I., Drozda, J., Normand, S. L., & Resnic, F. S. (2019). Comparative safety of aspiration thrombectomy catheters utilizing prospective, active surveillance of the NCDR CathPCI registry. Circulation: Cardiovascular Quality and Outcomes, 12(2), Article e004666. https://doi.org/10.1161/CIRCOUTCOMES.118.004666
    • Mehta, S. S., Adoni, N., Shihabi, A., Bodine, C., Moussa, I., & Gibb, M. (2019). Multimodality imaging and percutaneous closure of right sinus of valsalva to right ventricular outflow tract fistula after transcatheter aortic valve replacement. Journal of Invasive Cardiology, 31(7), E227-E228.
    • Valle, J. A., Tamez, H., Abbott, J. D., Moussa, I. D., Messenger, J. C., Waldo, S. W., Kennedy, K. F., Masoudi, F. A., & Yeh, R. W. (2019). Contemporary Use and Trends in Unprotected Left Main Coronary Artery Percutaneous Coronary Intervention in the United States: An Analysis of the National Cardiovascular Data Registry Research to Practice Initiative. JAMA Cardiology, 4(2), 100-109. https://doi.org/10.1001/jamacardio.2018.4376