Zeynep Madak-Erdogan


  • Title: Assistant Professor
  • Group: Multimodal Vascular Imaging
  • Status: Beckman Affiliate Faculty
  • Home: Food Science and Human Nutrition



Dr. Madak-Erdogan is an assistant professor in the Department of Food Sciences and Human Nutrition at the University of Illinois at Urbana-Champaign. She received her PhD in Cell and Developmental Biology from the University of Illinois in 2009 and her B.S. in Molecular Biology and Genetics from Bilkent University in 2002.


Mary Swartz Rose Young Investigator Award from American Society of Nutrition (2016); Scholars Travel Fund, Travel Award for presenting in ENDO meeting (2015); Scholars Travel Fund, Travel Award for presenting in Keystone Meeting (2015); Arnold O. Beckman Award (2015); ENDO Early Investigators Award (2015); Scholars Travel Fund, Travel Award (2015); Eugenia Rosemberg Memorial Fund, Abstract Travel Award (2015).


  • 2016
    • Chambliss, K.L.; Barrera, J.; Umetani, M., Umetani, J.; Kim, S.H.; Madak-Erdogan,3 Z.; Katzenellenbogen,1 B.S.; Katzenellenbogen, J.A.; Mineo, C. and Shaul, P.W., Non-Nuclear Estrogen Receptor Activation and Cardiometabolic Disease Protection, in press Endocrinology
    • Madak-Erdogan Z., Kim SH, Gong P, Zhao YC, Zhang H, Chambliss KL, Carlson KE, Mayne CG, Shaul PW, Korach KS, Katzenellenbogen JA, Katzenellenbogen1 BS. Design of pathway preferential estrogens that provide beneficial metabolic and vascular effects without stimulating reproductive tissues. Science Signaling 2016 May 24;9(429):ra53. PubMed PMID: 27221711.
    • Gong P.; Madak-Erdogan,3 Z., Flaws J.A.; Shapiro D.J., Katzenellenbogen J.A., and Katzenellenbogen,1 B.S.; Estrogen Receptor-a and Aryl Hydrocarbon Receptor Involvement in the Actions of Botanical Estrogens in Target Cells, Mol Cell Endocrinol. 2016 Aug 16. PMID:27543265.
    • Wrobel, K.U.; Zhao, Y.C.; Kulkoyluoglu, E.; Chen, KL.; Hieronymi K.; Holloway, J.; Li, S.; Ray, T.; Ray, P.S.; Lipka, A.E.; Smith, R.L.; Madak-Erdogan, Z.; XPO1 Regulates tamoxifen responsiveness in estrogen receptor positive breast tumors by decreasing nuclear localization of ERK5, Mol Endocrinol. 2016 Aug PMID:27533791.
    • Kulkoyluoglu E.; Madak-Erdogan Z.; Role of nuclear and extranuclear estrogen receptor signaling in breast cancer, Steroids. 2016 Jul 6. PMID:27394959.
    • Zhao YC, Madak Erdogan Z. Systems Biology of Metabolic Regulation by Estrogen Receptor Signaling in Breast Cancer. J Vis Exp. 2016 Mar 17;PubMed PMID: 27023311.
  • 2015
    • Madak-Erdogan,3 Z.; Gong, P., Katzenellenbogen,1 B.S., Differential Utilization of Nuclear and Extranuclear Receptor Signaling Pathways in the Actions of Estrogens, SERMs, and a Tissue- Selective Estrogen Complex (TSEC), J Steroid Biochem Mol Biol. 2015 Dec 12.
    • Madak-Erdogan,3 Z.*; Gong, P., Zhao, YC, Xu, L.; Wrobel, K.U.; Hartman, J., Wang, M. Cam, A. Doerge, D., Khan, I.A., Katzenellenbogen, J.A., Katzenellenbogen,1 B.S., Helferich, 1 W.G., Dietary licorice root supplementation improves menopause associated metabolic syndrome and provides resiliency to high-fat diet *Corresponding author, Mol Nutr Food Res. 2015 Nov 10.
    • Kim, S.H.; Madak-Erdogan,3 Z.; Bae, S.C.; Carlson, K.; Mayne, C.; Granick, S.; Katzenellenbogen,1 B.S.; Katzenellenbogen, J.A., Ligand Accessibility and Bioactivity of a Hormone-Dendrimer Conjugate, Journal of the American Chemical Society 2015 Aug 19;137(32):10326-35.
  • 2014
    • Gong P.*, Madak-Erdogan,3 Z.*, Li J., Cheng J., Greenlief M., and Katzenellenbogen,1 B.S. Transcriptome Analyses Reveal Distinct Patterns of Gene Regulation by Different Botanical Estrogens in Dietary Supplements, Nuclear Receptor Signaling Atlas 2014 Sep 12 PMID:25363786 *Equal contribution.
    • Bergamaschi, A., Madak-Erdogan,3 Z., Kim Y., Choi Y.L., Lu H. and Katzenellenbogen,1 B.S. The forkhead transcription factor FOXM1 promotes endocrine resistance and invasiveness in estrogen receptor-positive breast cancer by expansion of stem-like cancer cells., Breast Cancer Research. 2014 Sep 12;16(5):436. PMID:25213081.
    • Madak-Erdogan,3 Z., Ventrella R, Petry L., Katzenellenbogen1 BS, Novel Roles for ERK5 and Cofilin as Critical Mediators Linking ERalpha-Driven Transcription, Actin Reorganization and Invasiveness in Breast Cancer., Molecular Cancer Research, 2014 May;12(5):714-27, PMID: 24505128.
  • 2013
    • Jiang, Y., Gong, P., Madak-Erdogan,3 Z., Martin, T., Jeyakumar, M., Carlson, K., Khan, I., Smillie, T.J., Chittiboyina, A.G., Rotte S.C.K., Helferich, 1 W.G., Katzenellenbogen, J.A., Katzenellenbogen1, B.S., Mechanism Enforcing the Estrogen Receptor Beta-Selectivity of Botanical Estrogens, FASEB Journal 2013 Nov;27(11):4406-18, PMID: 23882126.
    • Madak-Erdogan,3 Z., Charn T.H, Jiang Y, Liu E.T., Katzenellenbogen J.A., Katzenellenbogen1, B.S., Integrative Genomics of Gene and Metabolic Regulation by Estrogen Receptors a and ß and Coregulators, Molecular Systems Biology 2013 Jun 18;9:676, PMID: 23774759.
    • Kim K*, Madak-Erdogan,3 Z., Katzenellenbogen1, B.S., A MicroRNA196a2 and TP63 Circuit Regulated by Estrogen Receptor-a and ERK2 that Controls Breast Cancer Proliferation and Invasiveness Properties, Hormones and Cancer. 2013 Apr;4(2):78-91, PMID: 23250869 , *Equal contribution.
  • 2012
    • Stossi F, Madak-Erdogan,3 Z, Katzenellenbogen1, B.S., ERK2 Acts Directly on Chromatin to Drive Macrophage-dependent Loss of Estrogen Receptor Alpha Expression in Breast Cancer Cells, Oncogene. 2012 Apr 5;31(14):1825-34, PMID:21860415.
    • Madak-Erdogan,3 Z., Katzenellenbogen1, B.S., Aryl Hydrocarbon Receptor Modulation of Estrogen Receptor-a-Mediated Gene Regulation by a Multimeric Chromatin Complex Involving the Two Receptors and the Coregulator RIP140, Toxicological Sciences. 2012 Feb;125(2):401-11, PMID:22071320.


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