Directory

Caterina Gratton's directory photo.

Caterina Gratton

(she/her/hers)

Associate Professor

Primary Affiliation

Brain Connectivity and Networks

Affiliations

Status Full-time Faculty

Home Department of Psychology

Phone

Email cgratton@illinois.edu

Address 2165 Beckman Institute, 405 North Mathews Avenue

  • Biography

    Caterina Gratton is an Associate Professor in Psychology at the University of Illinois at Urbana-Champaign and PI of the Gratton Lab, housed in the Beckman Institute. Gratton completed a postdoctoral fellowship in the Neurology department at Washington University in St. Louis. Gratton’s research focuses on the organization and function of human brain networks and how they contribute to goal-directed cognition. She is interested in how these systems vary across people and over the lifespan. Caterina Gratton uses a multifaceted approach, adopting a variety of human brain imaging methods, including functional magnetic resonance imaging (fMRI) and recordings from patients to study how brain systems function and change. She was named an American Psychological Society “Rising Star” in honor of this work.


    Education

    • B.S., psychology & neuroscience, University of Illinois at Urbana-Champaign, 2008

    • Ph.D., Helen Wills Neuroscience Program, University of California, Berkeley, 2013

  • Honors

    2023: Member, Center for Excellence in Computational Cognition (CoCo) - G Tech

    2023: FSU Provost’s Faculty Travel Grant

    2022: Society for Neuroscience Invited “Meet the Expert” Speaker

    2020-2021: Special Issue Editor, Current Opinion in Behavioral Sciences

    2018-present: Associate Editor, Network Neuroscience

    2017: American Psychological Society, Rising Star

    2017: Society for Neuroscience, Trainee Professional Development Award

    2015-2017: NIH/NINDS F32 National Research Service Award

    2014-2015: NIH/NINDS T32 National Research Service Award (WUSTL Neurology)

    2013: Society for Neuroscience Chapter Travel Award

    2010-2013: NDSEG Graduate Research Fellowship

    2008-2010: National Science Foundation Graduate Research Fellowship

    2008: University of Illinois Bronze Tablet 

    2008: Michael Coles Award: Brain and Cognitive Psychology Award

    2007-2008: Goldwater Foundation Scholarship 

    2007-2008: University of Illinois J. C. Weagant and W. G. Crist Memorial Scholarship 

    2006: University of Illinois Dad’s Library Award

    2004-2008: University of Robert Byrd Scholar

    2004-2008: University of Illinois Chancellor’s Scholar 

    2004-2005: FMC Award of Excellence (Scholarship)

    2004: National Merit Finalist

  • Research

    Research areas: 

    • Human brain organization

    • Cognitive Control

    • Individual differences

    Different regions of the brain interact with one another, forming large-scale networks. My lab is interested in studying the characteristics of these networks and how they vary — both over time within an individual and across people. We also study how networks can become disrupted in neurological and psychiatric disorders, such as Parkinson’s Disease. Recent projects have taken a particular focus on precisely measuring brain organization and function within individuals using “precision” fMRI methods. These methods have promise to provide new insights into human brain function.

  • 2024

    • Dworetsky, A., Seitzman, B.A., Adeyemo, B., Nielsen, A. N., Hatoum, A. S., Smith, D. M., Nichols, T. E., Neta, M., Petersen, S.E., Gratton, C. (2024). Two common and distinct forms of variation in human functional brain networks. Nature Neuroscience.
    • Kraus, B. T., Gratton, C. (in press). Shared principles for disentangling heterogeneity in neuroscience and psychopathology. Journal of Psychopathology and Clinical Science.
    • Butler, E. R., Miller, G. E., Samia, N., White, S., Gratton, C., Nusslock, R. (2024). Neuroimmune mechanisms connecting violence with internalizing symptoms: a high dimensional multi-modal mediation analysis. Human Brain Mapping
    • Gratton, C., Ladwig, Z., Perez, D. C. (in press). What do network approaches add to our understanding of prefrontal cortex and executive function?. In: Organization of Frontal Lobe Networks and Function: Localization and Interaction, edited by M. T. Banich, S. N. Haber, and T. W., Robbins. Strüngmann Forum Reports, vol. 35, J. R. Lupp, series editor. Cambridge, MA: MIT Press.
    • Hermosillo, R. J. M., Moore, L. A., Fezcko, E., Pines, A., Pines, A., Dworetsky, A., Conan, G., Mooney, M.A., Randolph, A., Adeyemo, B., Earl, E., Perrone, A., Morales Carrasco, C., Uriate-Lopez, J., Snider, K., Doyle, O., Cordova, M., Nagel, B. J., Ewing, S. W. F., Satterthwaite, T., Dosenbach, N.U.F.D, Gratton, C., Petersen, S.E., Miranda Dominguez, O., Fair, D.A. (2024). A Precision Functional Atlas of Network Probabilities and Individual-Specific Network Topography. Nature Neuroscience, 27(5), 1000-1013
    • Shenhav, A., Banich, M. T., Beste, C., Buschman, T. J., Friedman, N. P. Gratton, C., Koechlin, E., O’Doherty, J., Schuck, N., Wang, X. J., (in press). Integrative psychological, computational, and mechanistic approaches to frontal lobe function. In: Organization of Frontal Lobe Networks and Function: Localization and Interaction, edited by M. T. Banich, S. N. Haber, and T. W., Robbins. Strüngmann Forum Reports, vol. 35, J. R. Lupp, series editor. Cambridge, MA: MIT Press.
    • Siegel, J. S., Subramanian, S., Perry, D., Kay, B. , Gordon, E. M., Laumann, T., Reneau, R., Gratton, C. , Horan, C., Metcalf, N., Chacko, R., Schweiger, J., Wong, D., Bender, D., Padawar-Curry, J., Raison, C., Raichle, M., Lenze, E. J., Snyder, A. Z., Dosenbach, N. U. F., Nicol, G. (2024). Psilocybin desynchronizes brain networks. Nature.

    2023

    • Kraus, B.T., Zinbarg, R., Braga, R.M., Nusslock, R., Mittal, V., Gratton, C. (2023). Insights from personalized models of brain and behavior for identifying biomarkers in psychiatry. Neuroscience and Biobehavioral Reviews, 105259
    • Porter, A., Fei, S., Damme, K.S.F., Nusslock, R., Gratton, C.*, Mittal, V.A.* (2023). A meta-analysis of single vs. multimodal neuroimaging techniques in the classification of psychosis. Molecular Psychiatry, 1-15
    • Gordon, E.M., Chauvin, R.J., Van, A. N., Rajesh, A., Nielsen, A., Newbold, D. J., Lynch, C. J., Seider, N. A., Krimmel, S. R., Scheidter, K. M., Monk, J., Miller, R. L., Metoki, A., Montez, D. F., Zheng, A., Elbau, I., Madison, T., Nishino, T., Myers, M. J. , Kaplan, S., D’Andrea, C. B., Demeter, D. V., Feigelis, M., Barch, D. M., Smyser, C. D., Rogers, C. E., Zimmermann, J., Botteron, K. N., Pruett, J. R., Willie, J. T., Brunner, P., Shimony, J. S., Kay, B. P, Marek, S., Norris, S. A., Gratton, C., Sylvester, C. M., Power, J. D., Liston, C., Greene, D. J., Roland, J. L., Petersen, S. E., Raichle, M. E., Laumann, T. O., Fair, D. A., Dosenbach, N.U.F. (2023) A somato-cognitive action network alternates with effector regions in motor cortex. Nature, 1-9
    • Perez, D.R., Dworetsky, A., Braga, R.M., Beeman, M., Gratton, C. (2023) Hemispheric asymmetries of individual differences in functional connectivity. Journal of Cognitive Neuroscience, 35 (2), 200-225.
    • Pierce, J.E., Petro, N.M., Clancy, E., Gratton, C., Petersen, S.E., Neta, M. (2023). Specialized cingulo-opercular network activation in judging facial expressions in a slow reveal task. Neuroimage
    • Smith, D. M., Kraus, B. T., Dworetsky, A., Gordon, E.M., Gratton, C. (2023) Brain hubs defined in the group do not overlap with regions of high inter-individual variability. Neuroimage, 277, 120195.
    • Uddin, L. Q., Betzel, R. F., Cohen, J. R., Damoiseaux, J. S., De Brigard, F., Eickhoff, S. B., Fornito, A., Gratton, C., Gordon, E. M., Laird, A. R., Larson-Prior, L., McIntosh, A. R., Nickerson, L. D., Pessoa, L., Pinho, A. L., Poldrack, R. A., Razi, A., Sadaghiani, S., Shine, J. M., Yendiki, A., Yeo, B. T., Spreng, R. N. (2023). Controversies and progress on standardization of large-scale brain network nomenclature. Network Neuroscience, 1-111.

    2022

    • Ladwig, Z., Seitzman, B.A., Adeyemo, B., Yu, Y., Smith, D., Petersen, S.E., Gratton, C. (2022). BOLD cofluctuation ‘events’ are predicted from static functional connectivity. Neuroimage, 260 (15), 119476
    • Yu, Y., Gratton, C., Smith, D. M. (2022). From correlation to communication: disentangling hidden factors from functional connectivity changes. Network Neuroscience, 7 (2), 411-430.
    • Gratton, C., Nelson, S. M., Gordon, E. M. (2022). Brain-behavior correlations: two paths toward reliability [Invited Spotlight]. Neuron. 110 (9), 1446-1449
    • Ladwig, Z., Yu, Y., Gratton, C. (2022). Combined methods reveal task activation dynamics in human brain networks. PLOS Biology. 20 (8), e3001749
    • Porter, A., Nielsen, A.N., Dorn, M., Dworetsky, A., Edmonds, D., Gratton, C. (2023) Masked features of task states found in individual brain networks. Cerebral Cortex. 33 (6), 2879-2900

    2021

    • Zheng, A., Montez, D. F., Marek, S., Gilmore, A. W., Newbold, D. J., Laumann, T. O., Kay, B. P., Seider, N. A., Van, A. N., Hampton, J., M., Alexopolous, D., Scheidter, K. M., Miller, R. L., Schlaggar, B. L., Sylvester, C., Petersen, S. E., Greene, D. J., Shimony, J. S., Nelson, S. M., Wig, G. S., Gratton, C., McDermott, K., B., Raichle, M. E., Gordon, E. M., Dosenbach, N.U.F. (2021). Parallel hippocampal-parietal circuits for self- and goal oriented processing. PNAS.
    • Anderson, Z., Gratton, C., Nusslock, R. (2021). The value of hyperalignment to unpack neural heterogeneity in the precision psychiatry movement (Correspondence). Biological Psychiatry: Cognitive Neuroscience and Neuroimaging
    • Dworetsky, A., Seitzman, B. A., Adeyemo, B., Coalson, R.S., Neta, M., Petersen, S. E., Gratton, C. (2021). Probabilistic mapping of human functional brain networks. Neuroimage, 237, 118164
    • Gratton, C., Braga, R. M. (2021). Editorial Overview: Deep imaging of the individual brain: past, practice, and promise. Current Opinions in Behavioral Sciences.
    • Kraus, B. T., Perez, D. R., Ladwig, Z., Seitzman, B. A., Dworetsky, A., Petersen, S. E., Gratton, C. (2021). Network variants are similar between task and rest states. Neuroimage, 229, 117743
    • Smith, D. M., Perez, D. R., Dworetsky, A., Porter, A., Gratton, C. (2021). Light through the fog: Using precision fMRI to disentangle the neural substrates of cognitive control. Current Opinion in Behavioral Sciences, 40, 19-26.

    2020

    • Fair, DA, Miranda-Dominguez, O, Perrone, A, Earl, EA, Van, AN, Koller, JM, Feczko, E, Klein, RL, Mirro, AE, Hampton, JM, Adeyemo, B, Snyder, AZ, Nguyen, A, Laumann, TO, Gratton, C., Greene, DJ, Schlaggar, BL, Hagler, D, Watts, R, Garavan, H, Barch, DM, Casey, BJ, Nigg, JT, Petersen, SE, Dale, A, Feldstein-Ewing, SW, Nagel, BJ, Dosenbach, NUF (2020). Correction of respiratory artifacts in MRI head motion estimates. Neuroimage, 208, 116400
    • Gratton, C., Smith, D. M., Dorn, M. (2020). Digging deeper to chart the landscape of human brain development. Neuron, 106 (2), 209-211.
    • Kong, TS, Gratton, C., Low, KA, Tan, CH, Chiarelli, AM, Fletcher, MA, Zimmerman, B, Maclin, EL, Gratton, G, Fabiani, M. (2020) Age-related differences in functional brain network segregation are associated with a cascade of cerebrovascular, structural, and cognitive effects. Network Neuroscience, 1-26.
    • Seitzman, BA, Gratton, C., Marek, S, Raut, RV, Dosenbach, NUF, Schlaggar BL, Petersen SE, Greene DJ. (2020) A set of functionally-defined brain regions with improved representation of the subcortex and cerebellum. Neuroimage, 116290. bioRxiv. PubMed.
    • Gordon, E.M., Laumann, T. O., Marek, S., Raut, R. V., Gratton, C., Gilmore, A. W., Newbold, D. J., Greene, D. J., Coalson, R. S., Snyder, A. Z., Schlaggar, B. L., Petersen, S. E., Dosenbach, N. U. F. D., Nelson, S. M. (2020) Default mode network streams for coupling to language and controls systems. Proceedings of the National Academy of Sciences, 117 (29), 17308-17319
    • Gratton, C., Dworetsky, A., Coalson, R. S., Adeyemo, B., Laumann, T. O., Wig, G., Kong, T.S., Gratton, G., Fabiani, M., Barch, D. M., Tranel, D., Miranda-Dominguez, O., Fair, D. A., Dosenbach, N.U.F.D., Snyder, A.Z., Perlmutter, J.S., Petersen, S.E., Campbell, M.C. (2020). Removal of high frequency contamination from motion estimates in single-band fMRI saves data without biasing functional connectivity. Neuroimage, 217, 116866
    • Gratton, C., Kraus, B.T., Greene, D.J., Gordon, E.M., Laumann, T.O., Nelson, S. M., Dosenbach, N.U.F., Petersen, S.E. (2020). Defining individual-specific functional neuroanatomy for precision psychiatry (Invited Review). Biological Psychiatry.
    • Gratton, C., Mittal, V. A. (2020). Embracing the complexity of heterogeneity in schizophrenia: A new perspective from latent clinical-anatomical dimensions. (Invited Editorial). Schizophrenia Bulletin, 46 (6), 1337-1338
    • Greene, DJ, Marek, S, Siegel, JS, Gordon, EM, Gratton, C., Newbold, DJ, Ortega, M, Laumann, TO, Miller, DB, Zheng, A, Lopez, KC, Berg, JJ, Coalson, RS, Nguyen, AL, Dierker, D, Van, AN, Hoyt, CR, McDermott, KB, Norris, SA, Shimony, JS, Snyder, AZ, Nelson, SM, Barch, DM, Schlaggar, BL, Raichle, ME, Petersen, SE, Dosenbach, NUF. (2020). Individual specific and shared integrative zones of the human thalamus and basal ganglia. Neuron. 105(4):742-758. PMID: 31836321
    • Nielsen, AN, Gratton, C., Church, JA, Dosenbach, NUF, Black, KJ, Petersen, SE, Schlaggar, BL, Greene, DJ. (2020) Atypical functional connectivity in Tourette Syndrome differs between children and adults. Biological Psychiatry. bioRxiv. PubMed.
    • Okerstrom-Jezewski, K. L., Grafft, A., Denburg, N., Bruss, J., Deifelt Streese, C., Gratton, C., Tranel., D. (2020). How early damage to the dorsomedial prefrontal hub in human brain networks affects long term cognitive, behavioral, and neuroanatomical outcomes. Psychology and Neuroscience, 13 (3), 245

    2019

    • Betzel, R.F., Bertolero, M. A., Gordon, E.M., Gratton, C., Dosenbach, N.U.F., Bassett, D.S. (2019). The community structure of functional brain networks exhibits scale-specific patterns of variability across individuals and time. Neuroimage, 202, 115990. bioRxiv. PubMed.
    • Gilmore, AW, Nelson, SM, Laumann, TO, Gordon, EM, Berg, JJ, Greene, DJ, Gratton, C., Nguyen, AL, Ortega, M, Hoyt, C, Coalson, RS, Schlaggar, BL, Petersen, SE, Dosenbach, NUF, McDermott, KB. (2019). High-fidelity mapping of repetition-related changes in the parietal memory network. Neuroimage, 199, 427-439. PubMed.
    • Seitzman, BA*, Gratton, C.*, Laumann TO, Gordon EM, Adeyemo B, Dworetsky, A, Kraus, BT, Gilmore AW, Berg JJ, Ortega M, Nguyen, A, Greene DJ, McDermott KB, Nelson SM, Lessov-Schlaggar, CN, Schlaggar BL, Dosenbach NUF, Petersen SE. (2019). Trait-like variants of human functional brain networks. PNAS, 116 (45), 22851-22861. PubMed.

    2018

    • Gordon, EM, Lynch, CJ, Gratton, C., Laumann, TO, Gilmore, AW, Greene, DJ, Ortega, M, Nguyen, AL, Schlaggar, BL, Petersen, SE, Dosenbach, NUF, Nelson, SM (2018). Three distinct sets of connector hubs integrate human brain function. Cell Reports, 24(7), 1687-1695. PubMed
    • Gratton, C., Koller, JM, Shannon, W, Greene, DJ, Snyder, AZ, Petersen, SE, Perlmutter, JS, Campbell, MC. (2018). Emergent functional network effects in Parkinson disease. Cerebral Cortex, 6, 2509-2523 PubMed
    • Gratton, C., Laumann, TO, Nielsen, AN, Greene, DJ, Gordon, EM, Gilmore, AW, Nelson, SM, Coalson, RS, Snyder, AZ, Schlaggar, BL, Dosenbach, NUF, Petersen, SE (2018). Functional brain networks are dominated by stable group and individual factors, not cognitive or daily variation, Neuron, 98(2) 439-452. PubMed
    • Gratton, C., Sun, H, Petersen, SE. (2018). Control networks and hubs (Invited Review). Psychophysiology, 55 (3), e13032. PubMed
    • Marek, S, Siegel, JS, Gordon, EM, Raut, RV, Gratton, C., Newbold, DJ, Ortega, M, Laumann, TO, Miller, DB, Zheng, A, Lopez, KC, Berg, JJ, Coalson, RS, Nguyen, AL, Dierker, D, Van, AN, Hoyt, CR, McDermott, KB, Norris, SA, Shimony, JS, Snyder, AZ, Nelson, SM, Barch, DM, Schlaggar, BL, Raichle, ME, Petersen, SE, Greene, DJ, Dosenbach, NUF. (2018) Spatial and temporal organization of the individual human cerebellum. Neuron, 100 (4), 977-993. PubMed.
    • Nielsen, A, Greene, DJ, Gratton, C., Dosenbach, NUF, Petersen, SE, Schlaggar, BL (2018). Evaluating the prediction of brain maturity from functional connectivity after motion artifact de-noising. Cerebral Cortex. PubMed

    2017

    • Gordon, EM, Laumann, TO, Gilmore, AW, Newbold, DJ, Greene, DJ, Berg, JJ, Ortega, M, Hoyt-Drazen, C, Gratton, C., Sun, H, Hampton, JM, Coalson, RS, Nguyen, A, McDermott, KB, Shimony, JS, Snyder, AZ, Schlaggar, BL, Petersen, SE, Nelson, SM, Dosenbach NUF. (2017). Precision functional mapping of individual human brains. Neuron, 95 (4), 791-807. PubMed
    • Gratton, C., Yousef, S, Aarts, E, Wallace, D, D’Esposito, M, Silver, MA. (2017). Cholinergic, but not dopaminergic or noradrenergic, enhancement sharpens visual spatial perception in humans. Journal of Neuroscience, 37 (16), 4405-4415 PubMed

    2016

    • Gratton, C., Laumann, T, Gordon, E, Adeyemo, B, Petersen, S. (2016) Evidence for two independent factors that modify brain networks to meet task goals. Cell Reports, 17(5), 1276-1288. PubMed
    • Gratton, C., Neta, M, Sun, H, Ploran, EJ, Schlaggar, BL, Wheeler, ME, Petersen, SE, Nelson, SM. (2016) Distinct stages of moment-to-moment processing in the cinguloopercular and frontoparietal networks. Cerebral Cortex, 27 (3), 2403-2417. PubMed
    • Laumann, TO, Snyder, AZ, Mitra, AM, Gordon, EM, Gratton, C., Adeyemo, B, Gilmore, AG, Nelson, SM, Berg, JJ, Greene, DJ, McCarthy, JE, Tagliazucchi, E, Laufs, H, Schlaggar, BL, Dosenbach NUF, Petersen, SE. (2016) On the stability of resting state fMRI correlations. Cerebral Cortex, 27 (10), 4719-4732. PubMed

    2015

    • Arnemann, KL, Chen, AJW, Novakovic-Agopian, T, Gratton, C., Nomura, EM, D’Esposito M. (2015). Functional brain network modularity predicts response to cognitive training after brain injury. Neurology, 84 (15), 1568-1574. PubMed

    2014

    • Gratton, C.*, Lee, T*, Nomura, EM, D’Esposito, M. (2014). Perfusion MRI indexes variability in the functional brain effects of theta-burst transcranial magnetic stimulation. PLOS ONE, 9(7): e101430. PMCID: PMC4081571; PubMed
    • Sreenivasan, KK, Gratton, C., Vytlacil, J, D’Esposito, M. (2014) Evidence for working memory storage operations in perceptual cortex. Cognitive, Affective, and Behavioral Neuroscience, 14, 117-128 PubMed

    2013

    • Gratton, C., Sreenivasan, KK, Silver, MA, D’Esposito, M. (2013). Attention selectively modifies the representation of individual faces in the human brain. Journal of Neuroscience, 33, 6979-6989, PMCID: PMC3685582
    • Blumenfeld, R, Nomura EM, Gratton, C., D’Esposito M. (2013). Lateral prefrontal cortex is organized into parallel dorsal and ventral streams along the rostro-caudal axis. Cerebral Cortex, 23(10), 2457-66, PMCID: PMC3767956
    • Gratton, C., Lee, T, Nomura, EM, D’Esposito, M. (2013). The effect of theta-burst TMS on cognitive control networks measured with resting state fMRI. Frontiers in Systems Neuroscience, 7, 124. PMCID: PMC3874542
    • Li, L, Gratton, C., Fabiani, M, Knight, R. T. (2013). Age-related frontoparietal changes during the control of bottom-up and top-down attention: an ERP Study. Neurobiology of Aging. 34, 477-488. PMCID: PMC4090105 PubMed

    2012

    • Gratton, C.*, Nomura, EM*, Perez, F, D’Esposito, M. (2012). Focal brain lesions to critical locations cause widespread disruption of the modular organization of the brain. Journal of Cognitive Neuroscience, 24, 1275-1285. PMCID: PMC3575518

    2010

    • Nomura, EM, Gratton, C., Visser, RM, Kayser, A, Perez, F, and D’Esposito, M. (2010). Double dissociation of two cognitive control networks in patients with focal brain lesions. Proceedings of the National Academy of Sciences of the United States of America, 107(26), 12017-12022. PMCID: PMC2900657 PubMed
    • Li, L, Gratton, C., Yao, D, and Knight, RT. (2010). Role of frontal and parietal cortices in the control of bottom-up and top-down attention in humans. Brain research, 1344, 173-84. Elsevier B.V. PMCID: PMC2900444 PubMed

    2009

    • Gratton, C., Evans, KM, Federmeier, KD. (2009). See what I mean? An ERP study of the effect of background knowledge on novel object processing. Memory and Cognition. 37, 277-291. PMCID: PMC2682721