Ning Wang's directory photo.

Ning Wang


Primary Affiliation

Extracellular Vesicle Imaging and Therapy


Status Affiliate Faculty

Home Department of Mechanical Science and Engineering

Phone 265-0913



  • 2016

    • Muhamed, I., Wu, J., Sehgal, P., Kong, X., Tajik, A., Wang3, N. & Leckband4, D. E. E-cadherinmediated force transduction signals regulate global cell mechanics. Journal of Cell Science 2016, 129, 9, p. 1843-1854.


    • Barry, A. K., Wang3, N. &Leckband4, D. E. Local VE-cadherin mechanotransduction triggers longranged remodeling of endothelial monolayers. Journal of Cell Science 2015, 128, 7, p. 1341-1351.
    • Chowdhury, F., Li, I. T. S., Leslie, B. J., Do?anay, S., Singh, R., Wang, X., Seong, J., Lee, S. H., Park, S., Wang, N. & Ha, T. Single molecular force across single integrins dictates cell spreading. Integrative Biology (United Kingdom) 2015, 7, 10, p. 1265-1271
    • Kim, T. J., Joo, C., Seong, J., Vafabakhsh, R., Botvinick, E. L., Berns, M. W., Palmer, A. E., Wang3, N., Ha, T., Jakobsson4, E., Sun, J. & Wang, Y. Distinct mechanisms regulating mechanical forceinduced Ca2+ signals at the plasma membrane and the ER in human MSCs. eLife. 2015, 4, e04876.
    • Li, Y., Luo, S., Ma, R., Liu, J., Xu, P., Zhang, H., Tang, K., Ma, J., Zhang, Y., Liang, X., Sun, Y., Ji, T., Wang, N. & Huang, B. Upregulation of cytosolic phosphoenolpyruvate carboxykinase is a critical metabolic event in melanoma cells that repopulate tumors. Cancer Research 2015, 75, 7, p. 1191- 1196


    • Barry, A. K., Tabdili, H., Muhamed, I., Wu, J., Shashikanth, N., Gomez, G. A., Yap, A. S., Gottardi, C. J., De Rooij, J., Wang3, N. & Leckband4, D. E. a-Catenin cytomechanics - role in cadherindependent adhesion and mechanotransduction. Journal of Cell Science 2014, 127, 8, p. 1779-1791.
    • Ingber, D. E., Wang, N. & Stamenovic, D. Tensegrity, cellular biophysics, and the mechanics of living systems. Reports on Progress in Physics 2014, 77, 4, 046603
    • Poh, Y. C., Chen, J., Hong, Y., Yi, H., Zhang, S., Chen, J., Wu, D. C., Wang, L., Jia, Q., Singh, R., Yao, W., Tan, Y., Tajik, A., Tanaka, T. S. & Wang, N. Generation of organized germ layers from a single mouse embryonic stem cell. Nature Communications 2014, 5, 4000
    • Wang, N. et al Matrix softness regulates plasticity of tumour-repopulating cells via H3K9 demethylation and Sox2 expression. Nature Communications 2014, 5, 4619
    • Wang, N. Stem cell mechanics: Auxetic nuclei. Nature Materials 2014, 13, 6, p. 540-542
    • Wang, N. Stem cells go soft: Pliant substrate surfaces enhance motor neuron differentiation. Cell Stem Cell. 2014, 14, 6, p. 701-703. doi: 10.1016/j.stem.2014.05.007.


    • Seong, J., Tajik, A., Sun, J., Guan, J. L., Humphries, M. J., Craig, S. E., Shekaran, A., García, A. J., Lu, S., Lin, M. Z., Wang, N. & Wang, Y. Distinct biophysical mechanisms of focal adhesion kinase mechanoactivation by different extracellular matrix proteins. Proceedings of the National Academy of Sciences of the United States of America 2013, 110, 48, p. 19372-19377
    • Seong, J., Wang, N. & Wang, Y. Mechanotransduction at focal adhesions: From physiology to cancer development. Journal of Cellular and Molecular Medicine 2013, 17, 5, p. 597-604


    • Liu, J., Tan, Y., Zhang, H., Zhang, Y., Xu, P., Chen, J., Poh, Y. C., Tang, K., Wang, N. & Huang, B. Soft fibrin gels promote selection and growth of tumorigenic cells. Nature Materials 2012, 11, 8, p. 734-741
    • Minary-Jolandan, M., Tajik, A., Wang, N. & Yu, M. F. Intrinsically high-Q dynamic AFM imaging in liquid with a significantly extended needle tip. Nanotechnology 2012, 23, 23, 235704
    • Poh, Y. C., Shevtsov, S. P., Chowdhury, F., Wu, D. C., Na, S., Dundr, M. & Wang, N. Dynamic force-induced direct dissociation of protein complexes in a nuclear body in living cells. Nature Communications 2012, 3, 866
    • Tabdili, H., Langer, M., Shi, Q., Poh, Y. C., Wang3, N. & Leckband4, D. Cadherin-dependent mechanotransduction depends on ligand identity but not affinity. Journal of Cell Science 2012, 125, 18, p. 4362-4371.
    • Twiss, F., Le Duc, Q., Van Der Horst, S., Tabdili, H., Van Der Krogt, G., Wang3, N., Rehmann, H., Huveneers, S., Leckband4, D. E. & De Rooij, J. Vinculin-dependent Cadherin mechanosensing regulates efficient epithelial barrier formation. Biology Open. 2012, 1, 11, p. 1128-1140.
    • Wang, N. et al, Cellular and molecular bioengineering: A tipping point. Cellular and Molecular Bioengineering 2012, 5, 3, p. 239-253


    • Poh, Y.-C.; Na, S.; Chowdhury, F.; Ouyang, M.; Wang, Y.; Wang, N., Rapid Activation of Rac GTPase in Living Cells by Force Is Independent of Src. PLoS ONE 2009, 4, (11), e7886.
    • Wang, Y.; Wang, N., FRET and Mechanobiology. Integrative Biology 2009, 1, (10), 565-573.
    • Kim, T.; Seong, J.; Ouyang, M.; Sun, J.; Lu, S.; J., H.; Wang, N.; Y., W., Mechanical rigidity regulates Ca2+oscillation via RhoA signaling pathway in human mesenchymalstem cells. Journal of Cellular Physiology 2009, 218, (2), 285-93.