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Biography
Education
B.S., chemistry, California Institute of Technology, 1999
Ph.D., chemistry, Stanford University, 2005
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Honors
2018: Fellow of the Royal Society of Chemistry
2017: BK21–KAIST Lectureship Award, Korea Advanced Institute of Science and Technology
2017: Innovation Award, St. Louis Academy of Sciences
2016: Saint Louis Award, ACS St. Louis Section
2014: Organometallics Young Investigator Fellowship, ACS Division of Organic Chemistry
2014: Saltman Lectureship, Metals in Biology Gordon Research Conference
2013: NSF CAREER Award
2012: Undergraduate Research Mentor of the Year Award, Washington University
2012: Alfred P. Sloan Foundation Research Fellowship
2011: Outstanding Faculty Member Nominee, Freshman Class Council & First Year Center
2011: Sony Electronics Scholarship Award for Excellence in Teaching, Washington University
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Research
Research Interests:
Synthetic inorganic and organometallic chemistry applied to renewable energy catalysis and oxidative organic transformations
Development of bifunctional therapeutic and diagnostic agents for amyloid peptide disorders such as Alzheimer’s disease
Study of the role of transition metal ions in neurodegenerative diseases
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2018
- Rana, M., Cho, H. J., Roy, T. K., Mirica, L. M., & Sharma, A. K. (2018). Azo-dyes based small bifunctional molecules for metal chelation and controlling amyloid formation. Inorganica Chimica Acta, 471, 419-429. https://doi.org/10.1016/j.ica.2017.11.029
- Tang, F., Park, S. V., Rath, N. P., & Mirica, L. M. (2018). Electronic: Versus steric effects of pyridinophane ligands on Pd(III) complexes. Dalton Transactions, 47(4), 1151-1158. https://doi.org/10.1039/c7dt04366j
2017
- Bandara, N., Sharma, A. K., Krieger, S., Schultz, J. W., Han, B. H., Rogers, B. E., & Mirica, L. M. (2017). Evaluation of 64Cu-Based Radiopharmaceuticals that Target Aß Peptide Aggregates as Diagnostic Tools for Alzheimer's Disease. Journal of the American Chemical Society, 139(36), 12550-12558. https://doi.org/10.1021/jacs.7b05937
- Sharma, A. K., Schultz, J. W., Prior, J. T., Rath, N. P., & Mirica, L. M. (2017). Coordination Chemistry of Bifunctional Chemical Agents Designed for Applications in 64Cu PET Imaging for Alzheimer's Disease. Inorganic Chemistry, 56(22), 13801-13814. https://doi.org/10.1021/acs.inorgchem.7b01883
- Watson, M. B., Rath, N. P., & Mirica, L. M. (2017). Oxidative C-C bond formation reactivity of organometallic Ni(II), Ni(III), and Ni(IV) complexes. Journal of the American Chemical Society, 139(1), 35-38. https://doi.org/10.1021/jacs.6b10303
- Wessel, A. J., Schultz, J. W., Tang, F., Duan, H., & Mirica, L. M. (2017). Improved synthesis of symmetrically & asymmetrically: N -substituted pyridinophane derivatives. Organic and Biomolecular Chemistry, 15(46), 9923-9931. https://doi.org/10.1039/c7ob02508d