Annette McCoy's directory photo.

Annette McCoy

Associate Professor

Primary Affiliation

Computational Imaging


Status Affiliate Faculty

Home Department of Veterinary Clinical Medicine




  • Biography

    Annette McCoy is an associate professor in the Department of Veterinary Clinical Medicine and a board-certified equine surgeon with a Ph.D. in genetics.


    • B.S., animal science, Michigan State University
    • M.S., clinical sciences, Colorado State University
    • Ph.D, comparative and molecular biosciences, University of Minnesota
    • D.V.M, Michigan State University
  • Honors
    • 2013-2014: Doctoral Dissertation Fellowship, University of Minnesota
    • 2013: Burroughs Wellcome Fund ‘Becoming Faculty’ Workshop Invited Participant
    • 2013: Council of Graduate Students Travel Award, University of Minnesota 
    • 2012: Vaughn Larson Scholarship Award, University of Minnesota
    • 2011: AAEP Foundation Past Presidents’ Research Fellow 
    • 2010-2013: NIH T32 Training Grant in Comparative Medicine and Pathology (Univ of Minnesota) 
    • 2010: ACVS Resident’s Forum, 2nd place, Large Animal Clinical Research Presentations
  • Research

    Research interests:

    • Identifying genetic factors that play a role in performance and orthopedic disease in the horse; specifically, osteochondrosis, osteoarthritis, and the development of alternative gait patterns

    • Amnion and wound healing

    McCoy research orthopedic disease, addressing clinical issues in horses and using the species as a translational model for humans.

    Within the Beckman Institute, she collaborates with Mariana Kersh, an associate professor of mechanical science and engineering, to investigate the influence of early exercise on bone modeling and remodeling with the goal of fracture prevention in equine and human athletes. She is also investigating quantitative MRI sequences for early joint disease diagnosis in collaboration with Brad Sutton, a professor of bioengineering and the technical director of the Biomedical Imaging Center, and Bruce Damon, an adjunct professor of bioengineering and the co-director of the Carle Illinois Advanced Imaging Center.

    McCoy's highly interdisciplinary research aims to bring a biological perspective to biomechanics as well as imaging approaches to musculoskeletal disease.

  • 2024

    • Comparison of plasma l-lactate between jugular and cephalic veins in healthy and systemically ill horses using a point-of-care device Rhodes, A. D., Wilkins, P. A. & McCoy, A. M., Mar 1 2024, In: Journal of Veterinary Emergency and Critical Care. 34, 2, p. 131-134 4 p.
    • Ex vivo comparison of pin placement with patient-specific drill guides or freehand technique in canine cadaveric spines Guevara, F., Foss, K. D., Harper, T. A. M., Moran, C. A., Hague, D. W., Hamel, P. E. S., Schaeffer, D. J. & McCoy, A. M., Feb 2024, In: Veterinary Surgery. 53, 2, p. 254-263 10 p.


    • A smart coating with integrated physical antimicrobial and strain-mapping functionalities for orthopedic implants Zhang, Y., Cui, J., Chen, K-Y., Kuo, S. H., Sharma, J., Bhatta, R., Liu, Z., Ellis-Mohr, A., An, F., Li, J., Chen, Q., Foss, K. D., Wang, H., Li, Y., McCoy, A. M., Lau, G. W. and Cao, Q., May 2023, In: Science Advances. 9, 18, p. eadg7397
    • Ala vestibuloplasty improves cardiopulmonary and activity-related parameters in brachycephalic cats Gleason, H. E., Phillips, H., Fries, R., Keating, S., Hamel, P. and McCoy, A., May 2023, In: Veterinary Surgery. 52, 4, p. 575-586 12 p.
    • CT volumetric analysis permits comparison of tongue size and tongue fat in different canine brachycephalic and mesaticephalic breeds Song, A., Phillips, H., Oliveira, C. R. and McCoy, A. M., May 2023, In: Veterinary Radiology and Ultrasound. 64, 3, p. 429-438 10 p.
    • Effect of Firocoxib and Flunixin Meglumine on Large Colon Mural Thickness of Healthy Horses Bishop, R. C., Wilkins, P. A., Kemper, A. M., Stewart, R. M. and McCoy, A. M., Jul 2023, In: Journal of Equine Veterinary Science. 126, 104562.
    • Elastic Modulus and Its Relation to Apparent Mineral Density in Juvenile Equine Bones of the Lower Limb Moshage, S. G., McCoy, A. M. and Kersh, M. E., Aug 2023, In: Journal of Biomechanical Engineering. 145, 8, 081001.
    • Heart rate, arterial pressure and propofol-sparing effects of guaifenesin in dogs Hristova, T. S., Keating, S. CJ., McCoy, A. M., Strahl-Heldreth, D. E., Doodnaught, G. M., Sieja, K. M. and Swanson, K. S., Jan 2023, In: Veterinary Anaesthesia and Analgesia. 50, 1, p. 50-56 7 p.
    • Impact of periarticular osteophytes of the distal tarsus diagnosed in nonlame yearling Standardbred horses on racing performance McCoy, A. M. and Scolman, K. N., Oct 2023, In: Veterinary Surgery. 52, 7, p. 1050-1056 7 p.
    • Influence of feline brachycephaly on respiratory, gastrointestinal, sleep, and activity abnormalities Gleason, H. E., Phillips, H. and McCoy, A. M., Apr 2023, In: Veterinary Surgery. 52, 3, p. 435-445 11 p.
    • Multidose misoprostol pharmacokinetics and its effect on the fecal microbiome in healthy, adult horses Pfeifle, R. L., Ericsson, A. C., McCoy, A. M., Boothe, D. M., Wooldridge, A. A., Groover, E. S., Sierra-Rodriguez, T. and Lascola, K. M., Mar 2023, In: American journal of veterinary research. 84, 3
    • Novel genetic variant associated with globoid cell leukodystrophy in a family of mixed breed dogs Hammack, S., Hague, D. W., Vieson, M. D., Esdaile, E., Hughes, S. S., Bellone, R. R. and McCoy, A. M., Sep 1 2023, In: Journal of veterinary internal medicine. 37, 5, p. 1710-1715 6 p.
    • Plantar osteochondral fragments in young Standardbreds are associated with minimal joint inflammation at the time of surgical removal McCoy, A. M., Secor, E. J., Roady, P. J., Gray, S. M., Klein, J. and Gutierrez-Nibeyro, S. D., Jan 2023, In: Equine veterinary journal. 55, 1, p. 33-41 9 p.
    • Reliability in performance assessment creates a potential application of artificial intelligence in veterinary education: evaluation of suturing skills at a single institution Kuzminsky, J., Phillips, H., Sharif, H., Moran, C., Gleason, H. E., Topulos, S. P., Pitt, K., McNeil, L. K., McCoy, A. M. and Kesavadas, T., Aug 2023, In: American journal of veterinary research. 84, 8


    • Controversies in spine research: Organ culture versus in vivo models for studies of the intervertebral disc Tang, S. N., Bonilla, A. F., Chahine, N. O., Colbath, A. C., Easley, J. T., Grad, S., Haglund, L., Le Maitre, C. L., Leung, V., McCoy, A. M., Purmessur, D., Tang, S. Y., Zeiter, S. and Smith, L. J., Dec 2022, In: JOR Spine. 5, 4, e1235.
    • Effect of omeprazole and sucralfate on gastrointestinal injury in a fasting/NSAID model Bishop, R. C., Kemper, A. M., Wilkins, P. A. and McCoy, A. M., Jul 2022, In: Equine veterinary journal. 54, 4, p. 829-837 9 p.
    • Effects of a single dose of orally and rectally administered misoprostol in an in vivo endotoxemia model in healthy adult horses Kimura, S., McCoy, A. M., Boothe, D. M., Wooldridge, A. A., Graff, E., Hammack, S. M., Cresci, L., Hofmeister, E. and Lascola, K. M., Aug 2022, In: American journal of veterinary research. 83, 8
    • Kinetic Analysis in Horses With Deep Digital Flexor Tendinopathy Within the Digit Diagnosed by Magnetic Resonance Imaging Madsen, L. M., Gutierrez-Nibeyro, S. D., Stewart, M. C., McCoy, A. M. and Schaeffer, D. J., May 31 2022, In: Frontiers in Veterinary Science. 9, 893026.
    • Performance of predictive models of survival in horses undergoing emergency exploratory laparotomy for colic Bishop, R. C., Gutierrez-Nibeyro, S. D., Stewart, M. C. and McCoy, A. M., Aug 2022, In: Veterinary Surgery. 51, 6, p. 891-902 12 p.
    • Short-term administration of flunixin meglumine or firocoxib does not alter viscoelastic coagulation profiles in healthy horses Bishop, R. C., McCoy, A. M., Kemper, A. M., Stewart, R. M. and Wilkins, P. A., Dec 2022, In: Journal of the American Veterinary Medical Association. 260, 15, p. 1963-1966 4 p.
    • The effect of repeated freezing and thawing on the suture pull-out strength in equine arytenoid and cricoid cartilages Gray, S. M., Gutierrez-Nibeyro, S. D., Horn, G. P., McCoy, A. M., Schaeffer, D. J. and Stewart, M., Oct 2022, In: Veterinary Surgery. 51, 7, p. 1106-1110 5 p.


    • Biomechanical properties of canine staphylectomies closed with barbed or smooth suture Gleason, H. E., Phillips, H., McCoy, A. M., Gutierrez-Nibeyro, S. D., McKiernan, B. C., Duffy, D. J., Feign, I. M., Kim, W. J. and Kersh, M. E., Jan 2021, In: Veterinary Surgery. 50, 1, p. 196-206 11 p.
    • Comparison of basilar sesamoidean and distal approaches for synoviocentesis of the forelimb digital flexor tendon sheath in horses Slaughter-Mehfoud, K. M. and McCoy, A. M., Mar 2021, In: American journal of veterinary research. 82, 3, p. 225-229 5 p.
    • Evaluation of the airway mechanics of modified toggle laryngoplasty constructs using a vacuum chamber airflow model Gray, S. M., Gutierrez-Nibeyro, S. D., Couëtil, L. L., Horn, G. P., Kesler, R. M., McCoy, A. M., Stewart, M. C. and Schaeffer, D. J., Oct 2021, In: Veterinary Surgery. 50, 7, p. 1409-1417 9 p.


    • DDB2 Genetic Risk Factor for Ocular Squamous Cell Carcinoma Identified in Three Additional Horse Breeds Crausaz, M., Launois, T., Fleming, K. M., McCoy, A. M., Knickelbein, K. E. and Bellone, R. R., Dec 5 2020, In: Genes. 11, 12, p. 1-10 10 p., 1460.
    • Differential gene expression analysis reveals pathways important in early post-traumatic osteoarthritis in an equine model McCoy, A. M., Kemper, A. M., Boyce, M. K., Brown, M. P. and Trumble, T. N., Dec 2020, In: BMC genomics. 21, 1, 843.
    • Normal regression of the internal umbilical remnant structures in Standardbred foals Mccoy, A. M., Lopp, C. T., Kooy, S., Migliorisi, A. C., Austin, S. M. and Wilkins, P. A., Nov 1 2020, In: Equine veterinary journal. 52, 6, p. 876-883 8 p.
    • Temporal and spatial changes in bone accrual, density, and strain energy density in growing foals Moshage, S. G., McCoy, A. M., Polk, J. D. and Kersh, M. E., Mar 2020, In: Journal of the Mechanical Behavior of Biomedical Materials. 103, 103568.


    • Differential gene expression in articular cartilage and subchondral bone of neonatal and adult horses Kemper, A. M., Drnevich, J., McCue, M. E. and McCoy, A. M., Oct 2019, In: Genes. 10, 10, 745.
    • Effect of Preparation Method on the Protein Profile of Equine Amnion Dressings McCoy, A. M., Arrington, J. and Yau, P. M., Jun 7 2019, In: Journal of Proteome Research. 18, 6, p. 2676-2685 10 p.
    • Effects of 2 preparation methods and long-term storage on structural integrity and bacterial loads of equine amnion McCoy, A. M., Smith, R. L., Secor, E. J. and Roady, P. J., Feb 1 2019, In: Veterinary Surgery. 48, 2, p. 222-228 7 p.
    • Harnessing big data for equine health McCue, M. E. and McCoy, A. M., Jul 2019, In: Equine veterinary journal. 51, 4, p. 429-432 4 p.
    • Identification and validation of genetic variants predictive of gait in standardbred horses McCoy, A. M., Beeson, S. K., Rubin, C. J., Andersson, L., Caputo, P., Lykkjen, S., Moore, A., Piercy, R. J., Mickelson, J. R. and McCue, M. E., May 2019, In: PLoS genetics. 15, 5, e1008146.
    • Long-term outcome after stifle arthroscopy in 82 Western performance horses (2003–2010) McCoy, A. M., Smith, R. L., Herrera, S., Kawcak, C. E., McIlwraith, C. W. and Goodrich, L. R., 2019, In: Veterinary Surgery. 48, 6, p. 956-965 10 p.
    • Single-dose pharmacokinetics of orally and rectally administered misoprostol in adult horses Lopp, C. T., McCoy, A. M., Boothe, D., Schaeffer, D. J. and Lascola, K. M., Nov 2019, In: American journal of veterinary research. 80, 11, p. 1026-1033 8 p.
    • SNP-based heritability and genetic architecture of tarsal osteochondrosis in North American Standardbred horses McCoy, A. M., Norton, E. M., Kemper, A. M., Beeson, S. K., Mickelson, J. R. and McCue, M. E., Feb 1 2019, In: Animal genetics. 50, 1, p. 78-81 4 p.


    • Recent advances in conservative and surgical treatment options of common equine foot problems Gutierrez-Nibeyro, S. D., McCoy, A. M. and Selberg, K. T., Jul 2018, In: Veterinary Journal. 237, p. 9-15 7 p.


    • Developing a 670k genotyping array to tag ~2M SNPs across 24 horse breeds Schaefer, R. J., Schubert, M., Bailey, E., Bannasch, D. L., Barrey, E., Bar-Gal, G. K., Brem, G., Brooks, S. A., Distl, O., Fries, R., Finno, C. J., Gerber, V., Haase, B., Jagannathan, V., Kalbfleisch, T., Leeb, T., Lindgren, G., Lopes, M. S., Mach, N., da Câmara Machado, A., and 15 others, Jul 27 2017, In: BMC genomics. 18, 1, 565.
    • The scope of Big Data in one medicine: Unprecedented opportunities and challenges McCue, M. E. and McCoy, A. M., Nov 16 2017, In: Frontiers in Veterinary Science. 4, NOV, 194.


    • Heritability of recurrent exertional rhabdomyolysis in standardbred and thoroughbred racehorses derived from snp genotyping data Norton, E. M., Mickelson, J. R., Binns, M. M., Blott, S. C., Caputo, P., Isgren, C. M., McCoy, A. M., Moore, A., Piercy, R. J., Swinburne, J. E., Vaudin, M. and McCue, M. E., Nov 2016, In: Journal of Heredity. 107, 6, p. 537-543 7 p.
    • Identification and validation of risk loci for osteochondrosis in standardbreds McCoy, A. M., Beeson, S. K., Splan, R. K., Lykkjen, S., Ralston, S. L., Mickelson, J. R. and McCue, M. E., Jan 12 2016, In: BMC genomics. 17, 1, 41.


    • Animal Models of Osteoarthritis: Comparisons and Key Considerations McCoy, A. M., Sep 24 2015, In: Veterinary pathology. 52, 5, p. 803-818 16 p.
    • Short- and long-term racing performance of Standardbred pacers and trotters after early surgical intervention for tarsal osteochondrosis Mccoy, A. M., Ralston, S. L. and Mccue, M. E., Jul 1 2015, In: Equine veterinary journal. 47, 4, p. 438-444 7 p.


    • Evidence of positive selection for a glycogen synthase (gys1) mutation in domestic horse populations McCoy, A. M., Schaefer, R., Petersen, J. L., Morrell, P. L., Slamka, M. A., Mickelson, J. R., Valberg, S. J. and Mccue, M. E., Oct 2014, In: Journal of Heredity. 105, 2, p. 163-172 10 p.
    • Validation of imputation between equine genotyping arrays McCoy, A. M. and McCue, M. E., Feb 2014, In: Animal genetics. 45, 1, p. 153 1 p.


    • Articular osteochondrosis: A comparison of naturally-occurring human and animal disease McCoy, A. M., Toth, F., Dolvik, N. I., Ekman, S., Ellermann, J., Olstad, K., Ytrehus, B. and Carlson, C. S., Nov 2013, In: Osteoarthritis and Cartilage. 21, 11, p. 1638-1647 10 p.


    • Use of a radiofrequency probe for tenoscopic-guided annular ligament desmotomy McCoy, A. M. and Goodrich, L. R., Jul 2012, In: Equine veterinary journal. 44, 4, p. 412-415 4 p.


    • Pulmonary Gas Exchange and Plasma Lactate in Horses with Gastrointestinal Disease Undergoing Emergency Exploratory Laparotomy: A Comparison with an Elective Surgery Horse Population Mccoy, A. M., Hackett, E. S., Wagner, A. E., Mama, K. R. and Hendrickson, D. A., Jul 2011, In: Veterinary Surgery. 40, 5, p. 601-609 9 p.


    • Alimentary-associated carcinomas in five Vietnamese potbellied pigs McCoy, A. M., Hackett, E. S., Callan, R. J. and Powers, B. E., Dec 1 2009, In: Journal of the American Veterinary Medical Association. 235, 11, p. 1336-1341 6 p.


    • Haste does not always make waste: Expertise, direction of attention, and speed versus accuracy in performing sensorimotor skills Beilock, S. L., Bertenthal, B. I., McCoy, A. M. and Carr, T. H., Apr 2004, In: Psychonomic Bulletin and Review. 11, 2, p. 373-379 7 p.