Ling J. Meng's directory photo.

Ling J. Meng


Primary Affiliation

Computational Imaging


Status Affiliate Faculty

Home Department of Nuclear, Plasma and Radiological Engineering

Phone 333-3407



  • Biography

    Ling Meng is a professor in the Department of Nuclear, Plasma, and Radiological Engineering. Additionally, he is an affiliated professor in the Department of Bioengineering and affiliated faculty Member of the Beckman Institute for Advanced Science and Technology.


    • B.Sc., modern physics, University of Science and Technology of China, PRC, 1995

    • Ph.D., detector physics, University of Southampton, UK, 2001

  • Research

    Research Areas:

    • Bioimaging at Multi-Scale

    • Developing and applying advanced X-ray and gamma ray sensors with extreme spatial and spectral resolution approaching the physical limits. 

    • Developing advanced image formation techniques , such as artificial compound eye (ACE) gamma cameras and hybrid electronic and mechanical collimation, to dramatically improve the spatial resolution and sensitivity of future SPECT and PET imaging systems

    • Developing hyperspectral single photon imaging (HSPI) techniques that explores a broad EM spectrum from visible photons to gamma ray radiation to allow multi-functional, multi-tracer molecular imaging techniques, which could greatly broaden the horizon of nuclear imaging for diagnosis and therapeutic applications. 

    • Developing emerging imaging techniques, such as X-ray fluorescence CT (XFCT) and X-ray luminescence CT (XLCT) .

    Research Interests:

    • Biomedical imaging

    • Radiation detection and measurement

    Ling Meng has focused a number of his research efforts on the diagnosis and treatment of cancer. These include the development of various imaging techniques for tracking T-cells (a collaboration with Professor Ed Roy at UIUC), creating therapeutically-engineered neural stem cells for treating glioblastoma (a collaboration with Professor Michael Lesniak at Northwestern University), and the development and characterization of X-ray induced and nanoparticle-mediated cancer therapy.

    Meng has substantial experience in developing high-performance gamma-ray sensors and advanced
    radiological imaging techniques. Over the past 15 years, his research group has developed a wide range of SPECT, PET, and X-ray instrumentations with emphases on ultrahigh spatial resolution (sub-100um) and simultaneous (SPECT/MR, SPECT/CT) multi-modality imaging capabilities.

  • 2016

    • Groll, G., Kim, K., Dutta, J., Bhatia, H., Zhang, J. C., Wang, J. H., Shen, Z. M., Cai, L, Li, Q., and Meng, L. J. Hybrid Pixel-Waveform (HPWF) Enabled CdTe Detectors for Small Animal Gamma- Ray Imaging Applications. IEEE Transactions on Nuclear Sciences, accepted for publication on Aug. 25, 2016.


    • Groll, A., La Riviere, P. and Meng, L. J. Element Identification in Organic Samples Utilizing a Benchtop X-Ray Fluorescence Emission Tomography (XFET) System. IEEE Transactions on Nuclear Sciences, vol. 62, pp2310-2317, 2015.


    • Cai, L., Lai, X., Shen, Z., Chen, C. T. & Meng, L. J. MRC-SPECT: A sub-500 µm resolution MRcompatible SPECT system for simultaneous dual-modality study of small animals. Nuclear Instruments and Methods in Physics Research, Section A: Accelerators, Spectrometers, Detectors and Associated Equipment 2014, 734, PART B, p. 147-151.


    • Cai, L. and Meng, L. J. Hybrid pixel-waveform CdTe/CZT detector for use in an ultrahigh resolution MRI compatible SPECT system. Nuclear Instruments & Methods in Physics Research Section a- Accelerators Spectrometers Detectors and Associated Equipment, vol. 702, pp. 101-103, Feb 21 2013. DOI 10.1016/j.nima.2012.08.069
    • Fu, G., Meng, L. J., Eng, P., Newville, M., Vargas, P. and La Riviere, P. Experimental demonstration of novel imaging geometries for x-ray fluorescence computed tomography, Medical Physics, vol. 40 2013.
    • Mejia, J., Reis, M. A., Miranda, A. C. C., Batista, I. R., Barboza, M. R. F., Shih, M. C., Fu, G., Chen, C. T., Meng, L. J., Bressan, R. A. & Amaro, E. Performance assessment of the single photon emission microscope: High spatial resolution SPECT imaging of small animal organs. Brazilian Journal of Medical and Biological Research 2013, 46, 11, p. 936-942. DOI 10.1590/1414- 431X20132764
    • Meng, L. J., and Li, N. SPECT system optimization against a discrete parameter spacc. Physics in Medicine and Biology, Vol. 58(9), pp. 3037-59, 2013.
    • Yin, Y., Chen, X., Wu, H., Komarov, S., Garson, A., Li, Q., Guo, Q., Krawczynski, H., Meng, L. J. & Tai, Y. C. 3-D spatial resolution of 350 µm pitch pixelated CdZnTe detectors for imaging applications. IEEE Transactions on Nuclear Science 2013, 60, 1, p. 9-15.


    • Komarov, S., Yin , Y., Wu, H., Wen, J., Krawczynski, H., Meng, L-J., and Tai, Y. C. Investigation of the limitations of highly pixilated CdZnTe detector for PET applications. Physics in Medicine and Biology, 57 (2012) 7355-7380.
    • Reis, M. A. D., Mejia, J., Batista, I. R., Barboza, M. R. F. F. D., Nogueira, S. A., Wagner, J., Cabral, F. R., Davoglio, P. M. V. M., Abílio, V. C., Fu, G., Li, N., Meng, L. J., Shih, M. C., Chen, C. T., Amaro Junior, E. & Bressan, R. A. SPEM: a state-of-the-art instrument for high resolution molecular imaging of small animal organs. Einstein (São Paulo, Brazil) Apr 2012, 10, 2, p. 209-215.