Brian T. Cunningham
Primary AffiliationExtracellular Vesicle Imaging and Therapy
Prof. Cunningham has been a faculty member in the department of Electrical and Computer Engineering and the department Bioengineering at the University of Illinois at Urbana-Champaign since 2004, following a 15-year career in Industry. Prof. Cunningham’s technical focus is the utilization of photonics for biosensing in applications that include life science research, diagnostics, environmental monitoring, and pharmaceutical screening. He has over 85 issued US patents and over 188 peer reviewed journal publications. He is a Fellow of NAS, IEEE, OSA, RSC, AAAS, and AIMBE.
B.S., electrical and computer engineering, University of Illinois at Urbana-Champaign, 1986
M.S., electrical and computer engineering, University of Illinois at Urbana-Champaign, 1987
Ph.D., electrical and computer engineering, University of Illinois at Urbana-Champaign, 1990
2021: Everitt Award for Teaching Excellence (College of Engineering, UIUC)
2020: Fellow of RSC
2020: George Anner Award for Excellence in Undergraduate Teaching
2020: Intel Alumni Chair, Department of Electrical and Computer Engineering, University of Illinois at Urbana-Champaign
2020: Fellow, Royal Society of Chemistry
2019: Associate, Center for Advanced Study
2018: Andrew T. Yang Research Award
2018: Associate, Center for Advanced Studies
2018-2019: IEEE Photonics Society Distinguished Lecturer
2016: Fellow of AAAS
2014: National Academy of Inventors
2014: IEEE EMBS Technical Achievement Award
2013: IEEE Sensors Council 2013 Distinguished Lecturer
2013: Fellow of OSA
2010: Engineering Council Award for Excellence in Advising
2010: Medical Scholars Program Outstanding Advisor Award
2010: IEEE Sensors Council 2010 Technical Achievement Award
Sensor design and instrumentation
Finite Difference Time Domain Analysis
My research group is focused on the application of sub-wavelength optical phenomena and fabrication methods to the development of novel devices and instrumentation for the life sciences. The group is highly interdisciplinary, with expertise in the areas of microfabrication, nanotechnology, computer simulation, instrumentation, molecular biology, and cell biology. In particular, we are working on biosensors based upon photonic crystal concepts that can either be built from low-cost flexible plastic materials, or integrated with semiconductor-based active devices, such as light sources and photodetectors, for high performance integrated detection systems.
- H. Inan, M. Poyraz, F. Inci, M.A. Lifson, M. Baday, B.T. Cunningham, and U. Demirci, Photonic Crystals: Emerging biosensors for point-of-care applications. Chemical Society Reviews, Vol. 46, p. 366-388, 2017.
- R.E. Scherr, K.D. Laugero, D.J. Graham, B.T. Cunningham, L. Jahns, K.R. Lora, M. Reicks, and A.R. Mobley, Innovative techniques for evaluating behavioral nutrition interventions. Advances in Nutrition, 8, 113-125, 2017.
- G. See, M. Naughton, L. Xu, P.J.A. Kenis, and B.T. Cunningham, Enhanced emission of quantum dots embedded within the high-index dielectric regions of photonic crystal slabs. Applied Physics Letters, 2016, 108, 17, 171108-171110.
- H. Yu, H. Le, E. Kaale, K.D. Long, T. Layoff, S.C. Lumetta, and B.T. Cunningham, Characterization of drug authenticity using thin layer chromatography imaging with a mobile phone. Journal of Pharmaceutical and Biomedical Analysis, 125, 85-93, 2016.
- H.-Y. Wu, L. Liu, M. Lu, and B.T. Cunningham, Lasing emission from plasmic nano-dome arrays. Advanced Optical Materials, 4, 5, 708-714, 2016.
- L. Kwon, K.D. Long, Y. Wan, H. Yu, and B.T. Cunningham, Medical diagnostics with mobile devices: Comparison of intrinsic and extrinsic sensing. Biotechnology Advances, 34, 291-304, 2016.
- Q. Huang, J. Peh, P.J. Hergenrother, and B.T. Cunningham, Porous photonic crystal external cavity laser biosensor. Applied Physics Letters, 109, 7, 071103-071105, 2016.
- Y. Wan, J. Carlson, B. Kesler, W. Peng, P. Su, S. Al-Mulla, S.J. Lim, A. Smith, J. Dallesasse, and B.T. Cunningham, Compact characterization of liquid absorption and emission spectra using linear variable filters integrated with a CMOS imaging camera. Nature Scientific Reports, DOI:10.1038/srep29117, 2016.
- Y. Zhuo, J.S. Choi, T. Marin, H. Yu, B.A. Harley, and B.T. Cunningham, Quantitative imaging of cell membrane-associated mass density using photonic crystal enhanced microscopy (PCEM). Progress in Quantum Electronics, 50, 1-18, 2016.
- G.L. Damhorst, C. Duarte-Guevara, W. Chen, T. Ghonge, B.T. Cunningham, and R. Bashir, Smartphone-imaged HIV-1 reverse transcription loop-mediated isothermal amplification (RT-LAMP) on a chip from whole blood. Engineering, 2015, 1, 3, 324-335. DOI:10.15302/J-ENG-2015072.
- See, G. G.; Xu, L.; Naughton, M. S.; Tang, T. T.; Bonita, Y.; Joo, J.; Trefonas, P.; Deshpande, K.; Kenis, P. J. A.; Nuzzo, R. G.; Cunningham, B. T., Region Specific Enhancement of Quantum Dot Emission Using Interleaved Two-Dimensional Photonic Crystals. Applied Optics 2015, 54, (9), 2302-2308, DOI:10.1364/Ao.54.002302.
- Hu, H.; Zhuo, Y.; Oruc, M. E.; Cunningham, B. T.; King, W. P., Nanofluidic Channels of Arbitrary Shapes Fabricated by Tip-Based Nanofabrication. Nanotechnology 2014, 25, (45), DOI:Artn 455301 DOI:10.1088/0957-4484/25/45/455301.
- Zhuo, Y.; Hu, H.; Chen, W. L.; Lu, M.; Tian, L. M.; Yu, H. J.; Long, K. D.; Chow, E.; King, W. P.; Singamaneni, S.; Cunningham, B. T., Single Nanoparticle Detection Using Photonic Crystal Enhanced Microscopy. Analyst 2014, 139, (5), 1007-1015, DOI:10.1039/C3an02295a.
- Kwon, B.; Seong, M.; Liu, J. N.; Rosenberger, M. R.; Schulmerich, M. V.; Bhargava, R.; Cunningham, B. T.; King, W. P., Large Infrared Absorptance of Bimaterial Microcantilevers Based on Silicon High Contrast Grating. Journal of Applied Physics 2013, 114, (15), DOI: 10.1063/1.4825313.
- Chan, L. L.; George, S.; Ahmad, I.; Gosangari, S. L.; Abbasi, A.; Cunningham, B. T.; Watkin, K. L., Cytotoxicity Effects of Amoora Rohituka and Chittagonga on Breast and Pancreatic Cancer Cells. Evidence-Based Complementary and Alternative Medicine 2011 (Article ID 860605), 8 pages.
- Liu, J. N.; Schulmerich, M. V.; Bhargava, R.; Cunningham, B. T., Optimally Designed Narrowband Guided-Mode Resonance Reflectance Filters for Mid-Infrared Spectroscopy. Optics Express 2011, 19, (24), 24182-24197.
- Beckman researchers announced as 2022 Cancer Center at Illinois research grant recipients
- Cunningham discovers new ultra-sensitive biosensing technique to spot molecules that reveal cancer
- Cunningham develops fast, low-cost blood test for detecting early-stage liver cancer
- Beckman scientists accelerate cancer biomarker detection
- Cunningham on team to design digital detection technique that counts SARS-CoV-2 particles
- Study: Portable, point-of-care COVID-19 test could bypass the lab
- Cunningham works to personalize cancer diagnostics
- Bashir, Cunningham, and Lu receive three NSF RAPID grants to develop quicker test for COVID-19
- Inexpensive, portable detector identifies pathogens in minutes
- Brian Cunningham awarded a patent for development of a new form of microscopy
- U of I Researchers Developing Smartphone App For Coronavirus Testing