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Contact name: Sharlene Denos
Contact email: denos@illinois.edu

Title: “Functional regulation of 4D metabolic network between multienzyme glucosome condensates and mitochondria.”

Glucose metabolism is biochemically intertwined between energy metabolism and building block biosynthesis in living cells. However, it has not been investigated how its metabolic network is orchestrated to govern glucose flux in space and time. Dr. Kyoung will demonstrate that glucosome assemblies behave like liquid droplets in human cells and thus reversibly respond to environmental changes. In addition, Dr. Kyoung’s team characterizes the molecular architecture of the glucosome, which appears to be constructed from higher-ordered oligomeric structures of its scaffolder enzyme along with transient enzyme-enzyme interactions. It is important to note that enzymatic compositions of glucosomes are altered when they are spatially in proximity to mitochondria to functionally couple glycolysis with mitochondrial metabolism in human cells. Dr. Kyoung proposes that the subcellular localization-function relationship between glucosomes and mitochondria represents one of the fundamental principles by which 4-dimensional metabolic networks are not only dynamically but also efficiently regulated in living human cells.

Beckman researchers and staff members are invited to come have a free professional portrait taken. No sign-up necessary; photos are taken on a first-come, first-served basis.

Photography is happening in 5602 Beckman, just off the elevator on the fifth floor. Beckman will save your photo to be used in the Beckman directory and will also share it with your home unit, if you have one.

Beckman Outreach Coordinator Lexie Kesler will be on hand from 8:30 a.m. to noon to share various outreach opportunities available within the institute.

We recommend you wear business casual for your portrait, and aim to wear solid-color clothing with no patterns.

Contact name: Mollie Stevens
Contact email: mollie@illinois.edu
Contact phone: 217-244-2603

Join your colleagues this fall for informal conversation and coffee in the Beckman West Garden.

This Gather in the Garden Series will be from 10-10:30 a.m. every Tuesday.

Contact name: Margaret Browne Huntt
Contact email: mbrowne@illinois.edu

Are you on a personal diversity journey, but worry you may say the wrong thing? Let us help! The Cancer Center at Illinois and the Beckman Institute are partnering for a lunch ‘n learn event to discuss Verna Myers' book, “What if I Say the Wrong Thing?: 25 Habits for Culturally Effective People." Registrants will receive a complimentary copy of the book and a free lunch during the event. Register to attend by Wednesday, Sept. 13.

Contact name: Elena Romanova
Contact email: romanova@illinois.edu

Join us at noon on Wednesdays this fall for yoga with a view! All sessions are free and will be held in Beckman's fifth-floor tower room. All are welcome to bring their own mat! 

Contact name: Mollie Stevens
Contact email: mollie@illinois.edu
Contact phone: 217-244-2603

Join your colleagues this fall for informal conversation and coffee in the Beckman West Garden.

This Gather in the Garden Series will be from 10-10:30 a.m. every Tuesday.

Contact name: Jeanne N'Diaye
Contact email: jndiaye@illinois.edu

Two graduate students will present their research at the second Beckman Graduate Student Seminar of the fall semester: Saddam Hossain and Aravind Baby. Lunch will be provided to registered attendees. You may register here.

The event takes place Wednesday, October 4 at noon in 5602 Beckman Institute.

Contact name: Elena Romanova
Contact email: romanova@illinois.edu

Join us at noon on Wednesdays this fall for yoga with a view! All sessions are free and will be held in Beckman's fifth-floor tower room. All are welcome to bring their own mat! 

Contact name: Lexie Kesler
Contact email: lkesler@illinois.edu

Come find out more about the Beckman Institute for Advanced Science and Technology! Learn about the barrier-busting interdisciplinary research facility and community of innovation. Tours will be offered the first Thursday of the month from 10-10:30 a.m.

Contact name: Stacy Olson
Contact email: srolson@illinois.edu
Contact phone: 217-244-8373

Beckman-Brown Lecture on Interdisciplinary Science

Professor Emery N. Brown, M.D., Ph.D. is the Edward Hood Taplin Professor of Medical Engineering and Computational Neuroscience at MIT; the Warren M. Zapol Professor of Anesthesia at Harvard Medical School; and an anesthesiologist at Massachusetts General Hospital.

His talk is titled, "General Anesthesia, Neuromodulation and Altered States of Arousal."

The annual Beckman-Brown Lecture on Interdisciplinary Science honors Dr. Arnold O. Beckman, the founder of the Institute, and Dr. Theodore “Ted” Brown, the founding director. The series is funded by a gift from the Arnold and Mabel Beckman Foundation. Learn more.

Contact name: Mollie Stevens
Contact email: mollie@illinois.edu
Contact phone: 217-244-2603

Join your colleagues this fall for informal conversation and coffee in the Beckman West Garden.

This Gather in the Garden Series will be from 10-10:30 a.m. every Tuesday.

Contact name: Elena Romanova
Contact email: romanova@illinois.edu

Join us at noon on Wednesdays this fall for yoga with a view! All sessions are free and will be held in Beckman's fifth-floor tower room. All are welcome to bring their own mat! 

Contact name: Mollie Stevens
Contact email: mollie@illinois.edu
Contact phone: 217-333-3287

Fan Lam will present: "Multiscale, Multiparametric Biochemical Imaging of the Brain." Fan, is an assistant professor in the Department of Bioengineering at UIUC, a full-time faculty member with the Beckman Institute and the director of the Master of Science in Biomedical Image Computing (MS-BIC) program.  

The seminar will be held at noon on Thursday, October 12 in Beckman Institute, room 1005. Lunch will be provided to registered attendees. You can register here.

Contact name: Mollie Stevens
Contact email: mollie@illinois.edu
Contact phone: 217-244-2603

Join your colleagues this fall for informal conversation and coffee in the Beckman West Garden.

This Gather in the Garden Series will be from 10-10:30 a.m. every Tuesday.

Contact name: Elena Romanova
Contact email: romanova@illinois.edu

Join us at noon on Wednesdays this fall for yoga with a view! All sessions are free and will be held in Beckman's fifth-floor tower room. All are welcome to bring their own mat! 

Contact name: Molly Stevens
Contact email: mollie@illinois.edu

Join members of the Beckman community for coffee and cookies in the Beckman Atrium. The Cookie Collab is scheduled for 3 p.m. on the third Thursday of each month. 

Contact name: Paritosh Gargya
Contact email: paritosh@illinois.edu

Title: “Computational understanding of biological patterns: 3D genome folding and landscape of stochastic cellular fate.”

Experimental measurements of chromosome conformation, epigenetic modifications, and stochastic cellular behavior present new opportunities for understanding fundamental biology. Dr. Liang will discuss how 3D polymer models using the CHROMATIX method and Hi-C chromosome conformation capture studies can identify a small set of non-random polymer interactions, which can drive chromatin folding. Large ensemble models of independently folded chromatin conformations can uncover hubs of many-body interactions, revealing novel mechanisms of promoter-enhancer interactions and gene regulation. Dr. Liang will then discuss the recent development of the ACME (accurate chemical master equation) method that can construct the exact time-evolving probabilistic landscapes of stochastic reaction networks by solving the underlying discrete chemical master equation. Examples of how these landscapes can be used to study cellular fate will be given. Finally, Dr. Liang will discuss how to meet the rising challenges of deciphering these newly computable high-dimensional probability landscapes and quantify their exact topological structures of peaks and cycles of various dimensions through persistent homology.