"Cell Surface Glycans as Cellular IDs" - Dr. Laura Kiessling (Beckman-Brown Lecture)
Laura Kiessling, professor of chemistry at MIT, presents the 2017 Beckman-Brown Lecture on Interdisciplinary Science.
Her talk focuses on the roles of carbohydrate-binding proteins in checking glycan IDs. Topics include probing the fundamental chemical forces underlying the recognition of carbohydrates to understanding how nature exploits these interactions to detect microbes. Kiessling's research combines tools from organic synthesis, polymer chemistry, structural biology, and molecular and cell biology.
The Annual Beckman-Brown Lecture on Interdisciplinary Science honors Dr. Arnold O. Beckman, the founder of the Institute, and Dr. Theodore “Ted†Brown, the founding director. The series is funded by a gift from the Arnold and Mabel Beckman Foundation.
The lecture was presented at the Beckman Institute on the University of Illinois at Urbana-Champaign campus on November 3, 2017.
Klaus Schulten Memorial Symposium - Session 5
Honoring the life and career of Dr. Klaus Schulten, professor of physics and leader in the field of computational biophysics, the symposium took place at the Beckman Institute on November 7-9, 2017.
**OPENING REMARKS**
[00:01-00:38] Zan Luthey-Schulten, University of Illinois (chair)
[00:38-16:37] Tamer Basar, Center for Advanced Study, Electrical and Computer Engineering, University of Illinois
[16:54-29:58] Jeffrey Moore, Director, Beckman Institute, University of Illinois
**SESSION 5**
[30:23-1:07:12] "In situ Structures of Molecular Complexes by Cryo-electron Tomography"
Peijun Zhang, University of Oxford
[1:07:12-1:44:36] "Large-scale Molecular Dynamics Simulations of Cadherin Complexes"
Marcos Sotomayor, Ohio State University
[1:45:20-2:11:25 ] "Magnetic Compass Sense of Migratory Birds: A Perspective"
Ilia Solov'yov, University of Southern Denmark
[2:11:59-2:39:09] "Building a Bridge from Molecular Simulation to Understand How Bacteria Work"
Peter Freddolino, University of Michigan
[ 2:39:33-3:17:24] "Computational Drug Discovery: From Proteome to Drugs"
Jerome Baudry, University of Alabama, Huntsville
[3:17:24-3:22:09] "Closing Remarks"
Organizing Committee: Zan Luthey-Schulten, Emad Tajkhorshid, Chris Chipot, and Alek Aksimentiev
For more information, please visit
go.illinois.edu/schulten
Klaus Schulten Memorial Symposium - Session 4
Honoring the life and career of Dr. Klaus Schulten, professor of physics and leader in the field of computational biophysics, the symposium took place at the Beckman Institute on November 7-9, 2017.
**SESSION 4**
[00:01-08:32] Video: Sculpting Proteins
[08:32-8:59] Alek Aksimentiev, University of Illinois (Chair)
"Molecular Mechanisms of Synaptic Neurotransmitter Release"
Axel T. Brunger, Stanford University and Howard Hughes Medical Institute
(Removed at presenter's request)
[09:41-49:36] "Over a Decade of Studying Membrane-protein Insertion"
James 'JC' Gumbart, Georgia Institute of Technology
[50:23-1:32:48]
"Molecular Simulation at the Mesoscale"
Rommie E. Amaro, University of California, San Diego
[1:32:48-1:35:19] Video: Klaus Schulten Memorial Video Tribute
"Opening Windows into the Cell: Bringing Structure to Cell Biology using Cryo-electron Microscopy"
Elizabeth Villa, University of California, San Diego
(Removed at presenter's request)
[1:35:36-2:17:54]"Molecular Simulations of Lipid Membrane Sensing and Remodeling Dynamics"
Gerhard Hummer, Max Planck Institute of Biophysics and Goethe University
[2:18:11-3:00:53] "Accurate Prediction of Membrane Permeabilities in Rational Lead Discovery"
Chris Chipot, University of Illinois and Centre National de la Recherche Scientifique
[3:00:59-3:27:12] "Closing Remarks"
Sir Anthony Leggett, University of Illinois and Nobel Laureate (2003, Physics)
For more information, please visit
go.illinois.edu/schulten
Klaus Schulten Memorial Symposium - Session 3
Honoring the life and career of Dr. Klaus Schulten, professor of physics and leader in the field of computational biophysics, the symposium took place at the Beckman Institute on November 7-9, 2017.
**OPENING REMARKS**
[00:01-00:47] Chris Chipot, University of Illinois (Chair)
[00:47-11:43] Mark Berger, NVIDIA Corporation
[11:43-15:39] William Gropp, National Center for Supercomputing Applications
[15:39-27:47] Laxmikant 'Sanjay' Kale, Computer Science, University of Illinois
**SESSION 3**
[28:17- 1:11:57] "Towards a Mechanistic Understanding of Ribosomal Function"
Helmut Grubmuller, Max Planck Institute for Biophysical Chemistry
"Physics of DNA and Chromatin Function"
Taekjip Ha, Johns Hopkins University
(Removed at presenter's request)
[1:12:29-1:49:58] "Molecular-level Description of Excitation Energy Transfer in Light-harvesting Systems"
Ulrich Kleinekathofer, Jacobs University Bremen
[1:50:52-2:24:54] "Computational Microscopy of Biological and Synthetic Nanopores"
Aleksei Aksimentiev, University of Illinois
For more information, please visit
go.illinois.edu/schulten
Klaus Schulten Memorial Symposium - Session 2
Honoring the life and career of Dr. Klaus Schulten, professor of physics and leader in the field of computational biophysics, the symposium took place at the Beckman Institute on November 7-9, 2017.
**SESSION 2**
[00:01-04:24] Attila Szabo, National Institutes of Health (Chair)
[04:24-50:32] "Cryo-electron Tomography or the Challenge of Doing Structural Biology in situ"
Wolfgang Baumeister, Max Planck Institute of Biochemistry
[50:32-1:30:33] "Using Computer Simulations to Advance our Understanding of Biological Systems at the Atomic Level"
Benoit Roux, University of Chicago
"Proton-coupled Electron Transfer in Enzymes and Photoreceptor Proteins"
Sharon Hammes-Schiffer, University of Illinois
(Removed at presenter's request)
[1:30:45-1:36:21] Video: Biophysical Society Interview
[1:36:53-2:13:40] "Klaus' Computational Microscope Applied to Harvesting, Transfer, and Trapping Solar Energy for Photosynthesis"
Neil Hunter, University of Sheffield
[2:13:44-2:47:55] "Reaction Paths, Stochastic Modeling, and the Mean First Passage Time"
Ron Elber, University of Texas at Austin
[2:48:45-3:27:36] "Capturing Biological Membranes and Membrane Proteins in Action Using Advanced Simulation Technologies"
Emad Tajkhorshid, University of Illinois
[3:27:48-3:37:41] "Closing Remarks"
Theodore 'Ted' Brown, Founding Director of the Beckman Institute, University of Illinois
For more information, please visit
go.illinois.edu/schulten
Klaus Schulten Memorial Symposium - Session 1
Honoring the life and career of Dr. Klaus Schulten, professor of physics and leader in the field of computational biophysics, the symposium took place at the Beckman Institute on November 7-9, 2017.
**OPENING REMARKS**
[00:01-06:00] Emad Tajkorshid, Beckman Institute, University of Illinois (Chair)
[06:00-12:55 ] James C. Phillips, Beckman Institute, NCSA
[12:55-21:51] Wen-Mei Hwu, Electrical and Computer Engineering, CSL
[21:51-30:11] John E. Stone, Beckman Institute
[30:11-34:27] Yann R. Chemla, Physics and NSF Center for the Physics of Living Cells
**SESSION 1**
[35:14-1:03:07] "Towards Simulating the Minimal Cell"
Zaida 'Zan' Luthey-Schulten, University of Illinois
[1:03:07-1:39:52] "Synergy Between NMR, Cryo-EM and Large-scale MD Simulations-An All-atom Model of a Native HIV Capsid"
Angela M. Gronenborn, University of Pittsburgh School of Medicine
[1:39:52-2:15:55] "Pursuing Klaus' Vision: Folding Chromatin Fibers by Mesoscale Simulations"
Tamar Schlick, New York University
[2:15:55-2:57:08] "Force Propagation in Biomolecular Complexes: in-vitro Meets in-silico"
Hermann E. Gaub, Ludwig-Maximilians-Universitat
[2:57:08-3:08:34] Video: Memorial Tribute by Tamar Schlick, NYU
For more information, please visit
go.illinois.edu/schulten
"Molecular Theranostics: An Imager's Perspective" - Dr. King Li (Director's Seminar)
Dr. King C. Li, the inaugural dean of the Carle Illinois College of Medicine and a member of the Bioimaging Science and Technology Group at the Beckman Institute, presents the Oct. 5, 2017, Beckman Institute Director's Seminar. In this Beckman Institute Director's Seminar, Dr. Li illustrates how an interdisciplinary team tackles the problem of targeted drug delivery and controlling the effects of therapeutic agents.
"The Future is For Everyone" - Podcast Producer Rose Eveleth (Lecture)
Producer, designer, writer and animator Rose Eveleth explores where science and technology come from, where they have taken us so far, and how to open the door for people who are imagining futures for everybody. Eveleth is best known for her work in BBC Future, Motherboard, Story Collider, and Lady Bits. She explores how humans tangle with science and technology and currently produces two highly-acclaimed podcasts, Flash Forward and ESPN's 30 for 30.
The lecture took place on Setpember 15, 2017 at the Beckman Institute for Advanced Science and Technology on the University of Illinois at Urbana-Champaign as was part of the 21st Century Scientists Working Group lecture series. For more information, please visit beckman.illinois.edu and 21centurysci.com.
60 Second Science: Stephen Boppart on Using Light to Diagnose Disease
Beckman Institute Bioimaging Science and Technology group member Stephen Boppart presents his research in sixty seconds.
As the head of the Biophotonics Imaging Laboratory at the Beckman Institute, Boppart uses light to image biological tissue and diagnose disease.
By combining optical imaging, biophotonics, and other advanced imaging techniques with clinical research, Boppart creates high-resolution, real-time, non-invasive images of biological tissue at the cellular and molecular level for diagnosing diseases such as cancer.
Boppart is a professor at the University of Illinois at Urbana-Champaign in the departments of Electrical and Computer Engineering and Bioengineering, and is affiliated with the Department of Internal Medicine in the College of Medicine, the Micro and Nanotechnology Laboratory, and the Institute for Genomic Biology.
