Aditi Das


  • Title: Associate Professor
  • Group: Molecular Design and Engineering
  • Affiliations: Extracellular Vesicle Imaging and Therapy
  • Status: Beckman Affiliate Faculty
  • Home: Comparative Biosciences



  • 2017
    • Roy, J., Pondenis, H., Fan T., Das, A., Comparative Proteomic Analysis of Metastatic and Non-metastatic Osteosarcoma of Human and Canine Origin. PLoS One, 2017, to appear.
    • Rouck, J.E., Bradley, WB., Kambalyal, A., Parayil, A. and Das, A., Expression and Purification of cytochrome P450 taxadiene 5alpha-hydroxylase in E.Coli, Protein Expression and Purification. Protein Expr Purif. 2017 Jan 18;132:60-67. DOI: 10.1016/j.pep.2017.01.008.
  • 2016
    • Plucinski, L., Gartia, M., Arnold, W., Ameen, A., Chang, T., Hsiao, A., Liu, G., Das, A., Substrate Binding to CYP2J2- Nanodiscs Detected by Nanoplasmonic Lygurcus Cup Arrays. Biosens Bioelectron. 2016, 337-46.
    • Lim, SJ, McDougle, D., Das, A. and Smith, A., Lipoprotein Nanoplatelets: Fluorescent, Zwitterionic Probes for Molecular and Cellular Imaging. Journal of the American Chemical Society, 2016, 138 (1), 64–67. DOI:10.1021/jacs.5b11225.
    • Arnold, W., Baylon, J, Tajkorshid, E. and Das, A., Asymmetric binding and metabolism of polyunsaturated fatty acids (PUFAs) by CYP2J2 epoxygenase. Biochemistry 2016, 55(50):6969-6980.
  • 2015
    • McDougle, D., Baylon, J. Meling D., Kambalyal, A., Tajkorshid, E., and Das, A., Incorporation of Charged Residues in the CYP2J2 F-G Loop Disrupts CYP2J2-Lipid Bilayer Interactions Biochimica et Biophysica Acta -Biomembranes 2015, 2060-2470.
    • Wilcox, K. C.; Marunde, M. R.; Das, A.; Velasco, P. T.; Kuhns, B. D.; Marty, M. T.; Jiang, H. M.; Luan, C. H.; Sligar, S. G.; Klein, W. L., Nanoscale Synaptic Membrane Mimetic Allows Unbiased High Throughput Screen That Targets Binding Sites for Alzheimer's-Associated a Beta Oligomers. Plos One 2015, 10, (4), DOI:UNSP e0125263 DOI:10.1371/journal.pone.0125263.

    • Roy, J. Pondenis, H., Fan T., Das, A., Direct Capture of Functional Proteins from Mammalian Plasma Membranes into Nanodiscs. Biochemistry, 2015, 6299–6302.
    • Zelasko, S, Meling, D., and Das A., A critical residue that controls the isomerization of prostaglandin in thromboxane synthase, Biophysical Chemistry, 2015, 34-40.
    • Zelasko, S., Arnold, W., Das, A., Endocannabinoid Metabolism by Cytochrome P450 Monooxygenases. Prostaglandins and Other Lipid Mediators. 2015, 116-117, 112-123.
  • 2014
    • McDougle, D., Kambalayal, A., Meling, D., and Das, A., Endocannabinoids - Anandamide and 2- Arachidonoylglycerol are Substrates for Human CYP2J2 Epoxygenase. J. Pharmacology and Experimental Therapeutics 2014, 616-627.
    • Meling, D., McDougle, D., and Das, A., CYP2J2 epoxygenase membrane anchor plays an important role in facilitating electron transfer from CPR. J. Inorganic Biochemistry 2014, 47-53.
    • Orlando, B., McDougle, D., Lucido, M., Eng, E., Stokes, D., Das, A., and Malkowski, M., Cyclooxygenase-2 Catalysis and Inhibition in Lipid Bilayer Nanodiscs. Archives of Biochemistry and Biophysics 2014, 546, 33-40
    • Srivarma, S., Mularcyzk, C. Meling, D., and Das, A., Substrate binding thermodynamics and kinetics to thromboxane synthase in model lipid bilayers. ChemBioChem 2014, 15, 892.
  • 2013
    • Zelasko S., Palaria, A., and Das, A., Modifications to produce high-level expression of mammalian cytochrome P450s in recombinant expression systems. Protein Expression and Purification 2013, 92, 77-87.
    • McDougle, D., Palaria, A., Magnetta E., Meling, D., and Das, ,A. Functional Studies of N-terminally modified CYP2J2 epoxygenase in Model Lipid Bilayers. Protein Science, 2013, 22, 964.
  • 2012
    • Marty, M., Das, A., Sligar, S.G., MALDI Mass Spectrometry of Membrane Proteins in Nanodiscs. Analytical Bioanalytical Chemistry 2012, 402: 721. DOI:10.1007/s00216-011-5512-3.


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